Notes on Family: Bunyaviridae

enveloped spheres

Contents

Members of this Family
General Description
Morphology
Genome
Genera in the Family
All Known Sequences
Curated Sequences

General Description

This family largely infects vertebrates and there are a small number of plant virus members, which form the genus Tospovirus. These have large (100nm diameter) enveloped particles, circular in cross section and containing a central core of ssRNA.

Morphology

Virions pleomorphic in shape and size, spheroidal and enveloped, 80-110 nm in diameter. 3 filamentous nucleocapsids per envelope, each 200-3000 nm long (depending on arrangement) and 2-2.5 nm in diameter. Symmetry helical.

Particles contain 1-2 % nucleic acid, over 50 % protein and 20-30 % lipid.

Genome

The genome consists of three negative or ambisense ssRNA segments, designated: L (large), M (medium) and S (small). The terminal nucleotide sequences of each segment are complementary, so that the RNAs form non-covalently closed circles.

Genera in the Family