Notes on Genus: Alphavirus

enveloped spheres

Type member: Sindbis virus

Contents

Members of this Genus
General Description
Morphology
Electron Micrograph
Genome
Genus Genomic Organization
Genome Map
Type Member Genomic Organization
Curated Sequences

General Description

This is one of two genera in the family Togaviridae and consists of those viruses with a genome of 11-12kb that encodes four structural proteins (coat protein and three membrane proteins). Members multiply in their insect vectors.

Morphology

Virions enveloped and spherical about 70 nm in diameter and with glycoprotein spikes. There are four structural proteins (coat protein and three membrane glycoproteins).

Genome

Monopartite positive sense single-stranded RNA 11-12kb in length, with a 5'-cap and a 3'-polyA tail.

Genus Genomic Organization

There are two polyproteins, the second of which is translated from a subgenomic RNA. They are subsequently processed into a number of functional proteins:

Type Member Genomic Organization

There are two polyproteins, the second of which is translated from a subgenomic RNA. They are subsequently processed into a number of functional proteins: