Notes on Genus: Aquaparamyxovirus

enveloped spheres

Type member: Atlantic salmon paramyxovirus

Contents

Members of this Genus
General Description
Morphology
Electron Micrograph
Genome
Genus Genomic Organization
Genome Map
Type Member Genomic Organization
Curated Sequences

General Description

The genus Aquaparamyxovirus is one of nine genera in the family Paramyxoviridae and contains contains viruses that infect fish (hence the name).

Morphology

Virions pleomorphic but usually spherical, enveloped, 150 nm in diameter or larger with spike-like projections.

Genome

Monopartite single-stranded negative sense RNA of about 17 kb. There is no genome-linked protein (VPg) at the 5'-terminus nor a 3'-polyA tail.

Genus Genomic Organization

There are 9 transcriptional elements (mRNA species) including a C protein. The V protein is produced from an edited transcript.

Type Member Genomic Organization

There are 9 transcriptional elements (mRNA species). Their major ORFs are listed here in their order on the template strand - i.e. from 3' to 5' with respect to the virion strand:
1    N59 kDa Coat protein (nucleocapsid)
2P 63 kDa Phosphoprotein
3C25 kDa Non-structural protein from same mRNA transcript as P but in a different reading frame
4V42 kDa Produced from the P transcript by RNA editing: shares the N-terminus of P but then has a frame shift
5W36 kDa Putatively produced from the P transcript by RNA editing: shares the N-terminus of P but then has a frame shift
6M39 kDa Matrix protein
7F 60 kDa Fusion protein: glycosylated envelope protein
8HN62 kDa Hemagglutinin-neuraminidase attachment protein
9L 249 kDa Polymerase