Notes on Genus: Carlavirus
Type member: Carnation latent virus
The genus Carlavirus
tent virus group) is one of the genera in the family Betaflexiviridae
and contains a large number of members or tentative members. In genome organisation it particularly resembles the genus Foveavirus
and members of the family Alphaflexiviridae
and is distinguished from them by having 6 ORFs and a large replication protein. Many of its members are transmitted by aphids in a non-persistent manner. Most members cause relatively mild symptoms.
Virions filamentous and slightly flexuous, not enveloped, 610-690 nm long and (10-)12-13(-15) nm in diameter. Nucleocapsids longitudinally striated (files of subunits separated by about four longitudinal furrows); symmetry helical with pitch of 3.3-3.4 nm.
Virions composed of 5-7 % nucleic acid.
Monopartite, linear, single stranded, positive sense RNA. 8.4-8.7 kb in length. The 3'- terminus has a poly(A) tract and the 5'- terminus sometimes has a methylated nucleotide cap, or a monophosphate.
Genus Genomic Organization
The RNA is translated from six putative open reading frames which are:
|1. || 219-223 kDa||Polymerase|
|2. ||25-26 kDa|| ||2-4. Triple gene block:|
probably involved in
|3. || 11-12 kDa|
|4. ||7-8 kDa|
|5. || 32-36 kDa||Coat protein|
|6. || 11-16 kDa||nucleic acid binding protein (NABP)|
Type Member Genomic Organization
There is no complete sequence for this virus, but other members of the genus have genomes of c.
8500 nucleotides. By analogy with other members, the RNA is probably translated from six open reading frames.