Notes on Genus: Ephemerovirus

enveloped bacilliform

Type member: Bovine ephemeral fever virus

Contents

Members of this Genus
General Description
Morphology
Electron Micrograph
Genome
Genus Genomic Organization
Genome Map
Type Member Genomic Organization
Curated Sequences

General Description

This is one of the animal virus genera in the family Rhabdoviridae. The genus is characterised by its bacilliform, enveloped, particles which contain a monopartite ssRNA genome that is more than 12kb in size. The name is taken from the type member.

Morphology

Virions are bullet- or cone-shaped, about 140-200 nm long and 60-80 nm in diameter.

Genome

Monopartite, linear, single-stranded, negative sense RNA, about 15000 nucleotides long.

Genus Genomic Organization

There are the five structural proteins common to all members of the family and several additional genes, encoding a tranmembrane glycoprotein and other proteins of unknown function, between the G and L genes.

Type Member Genomic Organization

The genes are listed here in their order on the template strand (i.e. from 3' to 5' with respect to the virion strand):
ORF  Gene     ProductFunction
1 N 49.1 kDaCoat protein (nucleocapsid)
2 P32.2 kDaPolymerase-associated phosphoprotein
3 P' 5.8 kdaP protein overlapping ORF2
4 M 25.5 kdaMatrix protein
5 G72.3 kda Glycoprotein
6 GNS68.8 kDaTransmembrane glycoprotein
7 alpha 110.7 kDaunknown function
8 alpha 214.2 kDaunknown function
9 alpha 35.7 kDaunknown function
10 beta12.3 kDaunknown function
11 gamma13.4 kDaunknown function
12 L249.8 kDa   Polyprotein with replicase and other functions