Notes on Genus: Ferlavirus

enveloped spheres

Type member: Fer-de-Lance paramyxovirus

Contents

Members of this Genus
General Description
Morphology
Electron Micrograph
Genome
Genus Genomic Organization
Genome Map
Type Member Genomic Organization
Curated Sequences

General Description

The genus Ferlavirus is one of nine genera in the family Paramyxoviridae and contains contains viruses that infect reptiles. The name is derived from the type species, Fer-de-Lance paramyxovirus.

Morphology

Virions pleomorphic but usually spherical, enveloped, 150 nm in diameter or larger with spike-like projections.

Genome

Monopartite single-stranded negative sense RNA of about 15 kb. There is no genome-linked protein (VPg) at the 5'-terminus nor a 3'-polyA tail.

Genus Genomic Organization

There are 8 transcriptional elements (mRNA species). There is no C protein and the phosphprotein P is produced from an edited transcript.

Type Member Genomic Organization

There are 8 transcriptional elements (mRNA species). Their major ORFs are listed here in their order on the template strand - i.e. from 3' to 5' with respect to the virion strand:
1    N51 kDa Coat protein (nucleocapsid)
2X 19 kDa Unkown ORF
3P 47 kDa Phosphoprotein produced by RNA editing
4V25 kDa Non-structural protein from same mRNA transcript as P but in a different reading frame
5M38 kDa Matrix protein
6F 58 kDa Fusion protein: glycosylated envelope protein
7HN62 kDa Hemagglutinin-neuraminidase attachment protein
8L 247 kDa Polymerase