Notes on Genus: Novirhabdovirus

enveloped bacilliform

Type member: Infectious hematopoietic necrosis virus

Contents

Members of this Genus
General Description
Morphology
Electron Micrograph
Genome
Genus Genomic Organization
Genome Map
Type Member Genomic Organization
Curated Sequences

General Description

This is one of the animal virus genera in the family Rhabdoviridae. The genus is characterised by its bacilliform, enveloped, particles which contain a monopartite ssRNA genome that is less than 12kb in size and with a non-viron (NV) protein encoded by a gene situated between the G and L genes. The name reflects the presence of the non-virion protein. The viruses infect fish.

Morphology

Virions are bullet- or cone-shaped, about 140-200 nm long and 60-80 nm in diameter.

Genome

Monopartite, linear, single-stranded, negative sense RNA, about 11000 nucleotides long.

Genus Genomic Organization

There are the five structural proteins common to all members of the family and an additional gene, encoding a protein that is not incorporated into the virus particle (hence non-virion NV), between the G and L genes.

Type Member Genomic Organization

The genes are listed here in their order on the template strand (i.e. from 3' to 5' with respect to the virion strand):
ORF  Gene     ProductFunction
1N 42.2 kDaCoat protein (nucleocapsid)
2P25.9 kDaPolymerase-associated phosphoprotein
3M 21.8 kdaMatrix protein
4G56.7 kda Glycoprotein
5NV13.2 kDaNon-virion protein of unknown function
6L225.2 kDa   Polyprotein with replicase and other functions