Notes on Genus: Ophiovirus

flexuous filaments

Type member: Citrus psorosis virus

Contents

Members of this Genus
General Description
Morphology
Electron Micrograph
Genome
Genus Genomic Organization
Genome Map
Type Member Genomic Organization
All Known Sequences
Curated Sequences

General Description

The genus Ophiovirus is the only genus in the family Ophioviridae and consists of viruses that have highly flexuous, fine filaments, rather resembling those in the genus Tenuivirus. These sediment as two components that encapsidate at least 3 and probably 4 RNAs. RNA3 encodes the coat protein in the negative sense. The name is derived from the snake-like appearance of the virions (Greek ophis = serpent).

Morphology

Fine, flexuous filaments of two lengths, c. 10 nm in diam. and of 2 lengths (300-500 and 1500-2500 nm) representing 'top' and 'bottom' sedimentation components. These are collapsed double-stranded forms of nucleocapsid-like, highly flexuous open circles formed of filaments 3-4 nm in diam. Top-component filaments have contour lengths of 600-1000 nm, i.e. twice that reported for the corresponding collapsed form. Bottom-component filaments had contour lengths c. 4 times longer than those of top component filaments.

Genome

Linear, single-stranded RNA in 4 components. The largest is about 7.5-8.0 kb and the others are in the range, 1.4 to 1.8 kb. Most (or perhaps all) proteins are encoded in the negative sense.

Genus Genomic Organization

In the completely sequenced members of the genus:

Type Member Genomic Organization

The virus has probably not been completely sequenced: