Notes on Genus: Orthoreovirus

icosahedra

Type member: Mammalian orthoreovirus

Contents

Members of this Genus
General Description
Morphology
Electron Micrograph
Genome
Genus Genomic Organization
Genome Map
Type Member Genomic Organization
Curated Sequences

General Description

This is one of the animal virus genera in the family Reoviridae. Members have 10 segments, particles more than 70 nm in diameter and sedimentation coefficients greater than 600S.

Morphology

Virions isometric (icosahedral), c.85 nm in diameter, with a double capsid shell surrounding a core of c.48 nm. Core particles have distinctive turrets at the fivefold axes.

Genome

Linear, double stranded RNA in 10 segments. Each virion contains a single copy of the entire genome. Total genome up to c.24000 nucleotides long.

Genus Genomic Organization

Most segments have a single ORF. The segments are usually labelled as large (L1-3), medium (M1-3) or small (S1-4) with reference to their mobility in electrophoresis.

Type Member Genomic Organization