Notes on Genus: Pefudensovirus
Type member: Periplaneta fuliginosa densovirus
This is one of the genera in the subfamily Densovirinae
, the insect pathogens in the family Parvoviridae
. Members are distinguished from those of the other genera by genome size (about 5.5 kb), genomic organisation and phylogenetic analysis. The name is from the type member, Pe
Virions isometric (icosahedral), not enveloped, 18-26 nm in diameter, made of 60 units of the capsid protein.
Linear, single-stranded monopartite DNA, about 5.5 kb long.
Genus Genomic Organization
There is an ambisense coding strategy. Three non-structural proteins are encoded in different ORFs in one sense (using a single mRNA promoter and leaky scanning). On the complementary strand, 3 ORFs are predicted but these are believed to be translated after splicing of mRNAs and by frameshift to yield the virion proteins.
Type Member Genomic Organization
There are 3 non-structural ORFs in one orientation (61.7, 33.1 and 30.6 kDa). The capsid proteins are encoded in the opposite orientation. Three ORFs (62.7, 25.9 and 19.8 kDa) are predicted but these are believed to be translated after splicing of mRNAs and by frameshift to yield the virion proteins.