Notes on Genus: Picobirnavirus

icosahedra

Type member: Human picobirnavirus

Contents

Members of this Genus
General Description
Morphology
Electron Micrograph
Genome
Genus Genomic Organization
Genome Map
Type Member Genomic Organization
Curated Sequences

General Description

This is currently the only genus in the family Picobirnaviridae. The name is derived from the Spanish pico (=small) with birna for bipartite RNA.

Morphology

Virions isometric (icosahedral), not enveloped, 35-40 nm in diameter.

Genome

Bipartite double-stranded RNA totalling 4-4.5 kb.

Genus Genomic Organization

The larger segment (A) has two or three ORFs, the last one of which is the coat protein. The single ORF of segment B encodes an RNA-dependent RNA polymerase that has similarities to that of picornaviruses.

Type Member Genomic Organization

Segment A (2.5 kb) encodes: Segment B (1.7 kb) encodes a 61 kDa protein that is an RNA-dependent RNA polymerase.