Notes on Genus: Sigmavirus

enveloped bacilliform

Type member: Drosophila melanogaster sigmavirus

Contents

Members of this Genus
General Description
Morphology
Electron Micrograph
Genome
Genus Genomic Organization
Genome Map
Type Member Genomic Organization
Curated Sequences

General Description

This is one of the animal virus genera in the family Rhabdoviridae. As in other genera, there are bacilliform, enveloped, particles which contain a monopartite ssRNA genome. Members infect invertebrates and are transmitted vertically through eggs and sperm. The name is taken from the type member.

Morphology

Virions are bullet- or cone-shaped, about 140-200 nm long and 75 nm in diameter.

Genome

Monopartite, linear, single-stranded, negative sense RNA, about 13000 nucleotides long.

Genus Genomic Organization

There are the five structural proteins common to all members of the family and an additional gene (X) encoding a protein of unknown function situated between the P and M genes.

Type Member Genomic Organization

The genes are listed here in their order on the template strand (i.e. from 3' to 5' with respect to the virion strand):
ORF  Gene     ProductFunction
1 N 50.8 kDaCoat protein (nucleocapsid)
2 P 35.3 kDaPolymerase-associated phosphoprotein
3 X 33.8 kda Protein of unknown function
4 M 25.8 kdaMatrix protein
5 G 63.4kda Glycoprotein
6 L 241.3 kDa   Polyprotein with replicase and other functions