Notes on Genus: Sigmavirus
Type member: Drosophila melanogaster sigmavirus
This is one of the animal virus genera in the family Rhabdoviridae
. As in other genera, there are bacilliform, enveloped, particles which contain a monopartite ssRNA genome. Members infect invertebrates and are transmitted vertically through eggs and sperm. The name is taken from the type member.
Virions are bullet- or cone-shaped, about 140-200 nm long and 75 nm in diameter.
Monopartite, linear, single-stranded, negative sense RNA, about 13000 nucleotides long.
Genus Genomic Organization
There are the five structural proteins common to all members of the family and an additional gene (X) encoding a protein of unknown function situated between the P and M genes.
Type Member Genomic Organization
The genes are listed here in their order on the template strand (i.e. from 3' to 5' with respect to the virion strand):
|ORF|| Gene ||Product||Function|
|1 ||N ||50.8 kDa||Coat protein (nucleocapsid) |
||35.3 kDa||Polymerase-associated phosphoprotein |
||X ||33.8 kda
||Protein of unknown function |
|4 ||M ||25.8 kda||Matrix protein |
||63.4kda ||Glycoprotein |
||241.3 kDa ||Polyprotein with replicase and other functions|