Notes on Genus: Tibrovirus

enveloped bacilliform

Type member: Tibrogargan virus

Contents

Members of this Genus
General Description
Morphology
Electron Micrograph
Genome
Genus Genomic Organization
Genome Map
Type Member Genomic Organization
Curated Sequences

General Description

This is one of the animal virus genera in the family Rhabdoviridae. The genus is characterised by its bacilliform, enveloped, particles which contain a monopartite ssRNA genome that is more than 12kb in size and which has a distinctive arrangement of ORFs. The name is taken from the type member.

Morphology

Virions are bullet- or cone-shaped, about 140-200 nm long and 60-80 nm in diameter.

Genome

Monopartite, linear, single-stranded, negative sense RNA, about 13300 nucleotides long.

Genus Genomic Organization

There are the five structural proteins common to all members of the family and three additional genes encoding proteins of unknown function, arranged as N-P-M-U1-U2-G-U3-L.

Type Member Genomic Organization

The genes are listed here in their order on the template strand (i.e. from 3' to 5' with respect to the virion strand):
ORF  Gene     ProductFunction
1 N 48.7 kDaCoat protein (nucleocapsid)
2 P 35.9 kDaPolymerase-associated phosphoprotein
3 M 28.9 kdaMatrix protein
4 U1 19.9 kDa Protein of unknown function
5 U2 17.1 kDa Protein of unknown function
6 G 76.8 kda Glycoprotein
7 U3 12.9 kDa Protein of unknown function
8L 244.3 kDa   Polyprotein with replicase and other functions