Notes on Genus: Trichomonasvirus

icosahedra

Type member: Trichomonas vaginalis virus 1

Contents

Members of this Genus
General Description
Morphology
Electron Micrograph
Genome
Genus Genomic Organization
Genome Map
Type Member Genomic Organization
All Known Sequences
Curated Sequences

General Description

This genus contains those members of the family Totiviridae that infect the protozoan parasite Trichomonas vaginalis (from which the genus name is derived). Members form a distinct phylogenetic cluster.

Morphology

Virions isometric, 36 nm in diameter.

Genome

Monopartite, linear, double stranded DNA of 4600-4900 base pairs.

Genus Genomic Organization

The genome has two large, overlapping ORFs on the positive strand:
1. 75-81 kDaCoat protein (gag)
2.   84-90 kDaPolymerase (pol): RNA-dependent RNA polymerase expressed as a fusion protein with gag by a ribosomal frameshift

Type Member Genomic Organization

There are two large, overlapping ORFs on the positive strand:
1. 75 kDaCoat protein (gag)
2.   86 kDaPolymerase (pol): RNA-dependent RNA polymerase expressed as a fusion protein with gag by a +1 ribosomal frameshift