Notes on Genus: Vitivirus

flexuous filaments

Type member: Grapevine virus A

Contents

Members of this Genus
General Description
Morphology
Electron Micrograph
Genome
Genus Genomic Organization
Genome Map
Type Member Genomic Organization
All Known Sequences
Curated Sequences

General Description

The genus Vitivirus is one of the genera in the family Betaflexiviridae. It contains viruses originally included tentatively in the genus Trichovirus, but which have five open reading frames, one of which is downstream of the coat protein cistron. The name is derived from the scientific name of grape, the host of the type member.

Morphology

Virions filamentous and flexuous, not enveloped, 725-825 nm long and 12 nm in diameter. Nucleocapsids are cross-banded, obliquely striated, and with rope-like features (depending on the negative staining method). The virions are composed of 5% nucleic acid.

Genome

Monopartite, linear, single stranded, positive sense RNA, 7400-7600 nucleotides long. The 3' terminus has a poly(A) tract and the 5' terminus has a methylated nucleotide cap.

Genus Genomic Organization

The genome is translated by means of 5 overlapping ORFs. The largest ORF (ORF1) is probably involved in replication. ORF3 is a putative movement protein, ORF4 is the coat protein and ORF5 is a putative RNA binding protein.

Type Member Genomic Organization

The genome is translated by means of 5 overlapping ORFs:
1    195 kDa Replication protein
2 19 kDa unknown function
3 31 kDa Movement protein
4 22 kDa Coat protein
5 10 kDa RNA binding protein