Sequence of DPV Leishmania RNA virus 1-4
Leishmania RNA virus 1-4 major capsid protein gene, complete cds, and putative RNA-dependent RNA polymerase gene, partial cds.
ACC No: U01899
Dated: 2006-11-14 | Length: 5283 | CRC: -1777506768
ID U01899; SV 1; linear; genomic RNA; STD; VRL; 5283 BP.
XX
AC U01899;
XX
DT 25-JAN-1994 (Rel. 38, Created)
DT 14-NOV-2006 (Rel. 89, Last updated, Version 11)
XX
DE Leishmania RNA virus 1-4 major capsid protein gene, complete cds, and
DE putative RNA-dependent RNA polymerase gene, partial cds.
XX
KW .
XX
OS Leishmania RNA virus 1 - 4
OC Viruses; dsRNA viruses; Totiviridae; Leishmaniavirus.
XX
RN [1]
RP 1-5283
RX PUBMED; 8122377.
RA Scheffter S., Widmer G., Patterson J.L.;
RT "Complete sequence of Leishmania RNA virus 1-4 and identification of
RT conserved sequences";
RL Virology 199(2):479-483(1994).
XX
RN [2]
RP 1-5283
RA Scheffter S.M.;
RT ;
RL Submitted (17-SEP-1993) to the EMBL/GenBank/DDBJ databases.
RL Scott M. Scheffter, Children's Hospital of Boston, Division of Infectious
RL Diseases, 300 Longwood Avenue, Boston, MA 02115, USA
XX
FH Key Location/Qualifiers
FH
FT source 1. .5283
FT /organism="Leishmania RNA virus 1 - 4"
FT /lab_host="Leishmania braziliensis guyanensis"
FT /mol_type="genomic RNA"
FT /clone="pBSLRV-7, pBSGAP, pBS190, pCR-D5"
FT /db_xref="taxon:12530"
FT stem_loop 1. .37
FT /note="conserved in virus isolate LRV1-1"
FT stem_loop 163. .189
FT /note="conserved in virus isolate LRV1-1"
FT stem_loop 214. .231
FT /note="conserved in virus isolate LRV1-1"
FT stem_loop 269. .284
FT /note="conserved in virus isolate LRV1-1"
FT stem_loop 403. .443
FT /note="conserved in virus isolate LRV1-1"
FT misc_signal 447. .453
FT /note="Kozak concensus site"
FT CDS 450. .2678
FT /codon_start=1
FT /product="major capsid protein"
FT /note="ORF2"
FT /db_xref="InterPro:IPR008871"
FT /db_xref="UniProtKB/TrEMBL:Q83100"
FT /experiment="experimental evidence, no additional details
FT recorded"
FT /protein_id="AAB50027.1"
FT /translation="MADIPNSDKIACGRKPMFCEIIKLANRKRLIFNTTDERVYDARLN
FT YCSTADSTVQADCHIYWRLKLRRTDAVFEEYTGQGYSLDTAAYPQQYTDIIRGYYSKHV
FT SSSLAANTQHCVNVVAMLRHAGACIAHYCMTGKIDCDIVSKKKHKNKEVVTLSNADSVS
FT FVAHSALYLPSPLRASDPEIFNMLYLLGCACDASIAMDNISNTSGAAKYSMPHYNPLQL
FT SHALHVTIFYMLSLMDSCGYGDDAVLALTSGLHSVTTVIAHSDEGGITRDALRELSYTQ
FT PYGTMPVPIAGYFQHINVLFTTQPAWDQFAGIWDYVILATAALVHLSDPGMTVNDVTYP
FT TTLTTKVATVDGRNSDLAAQMMHSATRFCDIFVENLSTFWGVVANPDGNASQALLHAFN
FT IVACAVEPNRHLEMNVMAPWYWVESSALFCDYAPFRSPISSAGYGPQCVYGARLVLAAT
FT NSLEFTGEPGDYSAYRFEWTTMRHNPLFNILNKRVGDGLANVDFRLRPFNEWLLEGQPS
FT RRSCNSAGHGTPTATCSHKTPNHDTLDEYIWGSTSCDLFHPAELTSYTTVCVRFRNYLS
FT GADGDVRILNTPTREVIEGNVVTRCDGIRCLDSNKRIQHVPEVARRYCMMARYLAQART
FT FGALTIGDDIIRGFDKVEKIVKMHKSNNRLDQMPLIDVTGLCQPMIETSTVRASTPTRI
FT DPNKLAAATARVELPLAPRCTSSLIPSSDTVPEPEPQVGETGDNGGCA"
FT variation 727
FT /replace="t"
FT variation 837
FT /replace="t"
FT variation 1512
FT /replace="c"
FT variation 1849
FT /replace="g"
FT variation 2146
FT /replace="g"
FT variation 2210
FT /replace="t"
FT variation 2520
FT /replace="a"
FT /note="clone pCRII-5'.F2"
FT variation 2582
FT /replace="g"
FT /note="clone pCRII-5'.F2"
FT CDS <2605. .5241
FT /codon_start=1
FT /standard_name="RDRP"
FT /product="RNA-dependent RNA polymerase"
FT /note="translation probably initiates at the 5' end of
FT major capsid protein coding sequence and results in the
FT expression of a fusion protein via a translational
FT frameshift"
FT /db_xref="GOA:Q83101"
FT /db_xref="InterPro:IPR001795"
FT /db_xref="UniProtKB/TrEMBL:Q83101"
FT /inference="non-experimental evidence, no additional
FT details recorded"
FT /protein_id="AAB50028.1"
FT /translation="SHHLIQYPNQSLKLAKPVTTEAALDCFENVRRMISGFLNLSWLTV
FT TSKERQHKSDSNYFYDYNLFFSQMPAIVFNQLKCCVKTQVDDAIKTILQKTKKVEPSKQ
FT VERTLTLSVLNTFLGYLDLGRYVTQYTEQQSGPVAAKLLLTLLSSALIALVPAKSDPNL
FT CQNKIPRHYYQLKAHVGAQKKVNLTAIEVIRGCQHECSVVYCEYMRYSAYFSGLYDDQV
FT AAILLYATAAHGVQGFGARFSILWALTCVKAPDFADEINIYIKHRGMSGLLPQLVEMKC
FT LLGRGVSEIDVELEARNRLNVKNLNMQKFNEDELRAAVRQVYSEEIRRSVSYPPICDFW
FT SSRWLWAANGSHSRALEHAHPELATRKEGQAYRKAVMEQWQHNPMDRWDGTVYVTPSAK
FT LEHGKTRLLLACDTLSYMWFEYALRPVERIWENSNVILDPGSIGNCGIAARVNKWRNSV
FT RGQSFFAVDYDDFNSQHTLLSQKIVFEELFQHINCNMSWTRTLIDSFDSMELWVKGKRA
FT GVVAGTLMSGHRATSFINSVLDRAYIICAGGHVPTSMHVGDDILMSCTFDHADNLIANL
FT TENGIRLNASKQVFSKTSGEFLRVAHREHTSHGYLARVVSSAVSGNWVSDHTLNQQEAL
FT MNATVCCRGILNRSLPGDKNPVVRVISRSVSKRTKVDERIIRLLLSGKACLRGGVVYGE
FT QTNCIQVYKINCRVERLEEKLPPYKHATEDYLNNHLTGIEVMAVRQYGSDIADIMAQAS
FT WKKSMSNESAEEISRLSLSRDKNLPCLYCITEDEVATLPVRYGLFTSYPILMMLKDRMP
FT IKEALKLAITVGYRPQPNSDIELDLWGESKNSCAIEGILPYNEATSMAQKLPCGGVVIQ
FT VIHNVYV"
FT stem_loop 2623. .2659
FT /function="possible role in translational frameshifting"
FT /note="possible pseudoknot formed with adjacent
FT nucleotides"
FT variation 2652
FT /replace="c"
FT /note="clone pCR-G2.R3"
FT variation 2654
FT /replace="g"
FT /note="clone pCRII-G2.R3"
FT variation 2966
FT /replace="c"
FT /note="clone pCRII-E1.T12"
FT variation 2967
FT /replace="t"
FT /note="clone pCRII-E1.T12"
FT variation 3054
FT /replace="a"
FT /note="clone pCRII-E1.T12"
FT misc_binding 3796. .3819
FT /bound_moiety="purines"
FT /note="conserved in virus isolate LRV1-1"
FT variation 3819
FT /replace="c"
FT /note="clone pCRII-E1.T12"
FT variation 4219
FT /replace="a"
FT /note="clone pCRII-E3.3'"
FT variation 4520
FT /replace="t"
FT /note="clone pCRII-E3.3'"
FT variation 5037
FT /replace="a"
FT /note="clone pCRII-E3.3'"
FT stem_loop 5206. .5245
FT /note="conserved in virus isolate LRV1-1"
FT stem_loop 5255. .5280
FT /note="conserved in virus isolate LRV1-1"
XX
SQ Sequence 5283 BP; 1466 A; 1135 C; 1304 G; 1378 T; 0 other;
u01899 Length: 5283 14-NOV-2006 Type: N Check: 8734 ..
1 gcgaattcaa acgagatgcc taagagtttg gattcgctag ctgtccggat
51 ggtagtgtta cctgtggtcc accacggtaa agcattaagg gctagcctta
101 acctcactgg aattgaatga aagtgggaga tcagtggcct ccaacggttg
151 gactgactgg acggggggta atcgagtggg agtcccccac atcctacatt
201 tatgtagttc ctcacgatcc acagcaatcg tctggttgta tccaggttac
251 tgccgcgagc gtaagggagt gttttggcag acacaatcca atatgctgac
301 tacggtcggt gtggaggatc cgaaacgtaa gcaagtttct tgttactatt
351 gatcaacagc tacatcctac aacgacagct atcataccag ccatctttaa
401 cccaagaatt ccacgtgaac ataccttgag tatacaattc ttgagcaaaa
451 tggctgatat accaaactct gataagattg cttgcggtcg caagcctatg
501 ttttgcgaga ttataaaact tgcaaacagg aagaggttga tctttaatac
551 aaccgacgag cgtgtgtatg atgcgcgatt gaactattgt tcaaccgcag
601 attctacagt gcaagcagat tgccacatct actggcgact caaactgcga
651 cgcactgatg cagtttttga ggaatacacc ggtcaagggt attcacttga
701 cactgctgct tacccacaac agtacactga tattatcaga gggtattaca
751 gtaagcacgt atcaagctct ctcgctgcaa acactcaaca ttgtgtgaac
801 gttgtggcta tgctacgcca tgctggtgca tgtatcgcac attattgcat
851 gactgggaaa attgattgtg acattgtgag taagaaaaaa cataaaaata
901 aagaggtggt gaccttgagc aatgctgaca gtgtgagttt tgtggctcac
951 tcggccttat atctgccttc tcctttacgt gccagcgatc ctgaaatctt
1001 taatatgtta tatttgcttg ggtgcgcttg tgacgctagt attgctatgg
1051 ataacatctc aaatacaagc ggggccgcta agtactcaat gccccattat
1101 aacccgctgc agctgtctca tgctctgcat gtgacgatat tttacatgtt
1151 aagcttgatg gacagctgcg ggtatggtga tgacgccgtc ctggcactaa
1201 cttctggctt acattccgtg accacagtta ttgcacacag tgatgaaggt
1251 ggtattacac gtgatgccct acgggaactg tcatacacgc aaccttatgg
1301 tactatgcct gtcccgattg ccggttactt ccagcacatt aacgtgctgt
1351 ttaccacaca gcccgcttgg gatcaatttg ctgggatttg ggattatgtt
1401 atcttggcga ctgctgctct ggtacatcta tctgatcctg gaatgactgt
1451 caacgatgtt acttacccta cgactctgac aactaaagtg gcaacggttg
1501 atgggcgtaa tagtgacttg gctgctcaga tgatgcacag cgcaacccga
1551 ttctgtgaca tattcgtgga gaatttaagc acattctggg gcgttgttgc
1601 taaccctgac gggaacgcaa gccaggctct actccacgct ttcaacatcg
1651 tggcttgtgc tgtagagccg aacagacatc tggagatgaa tgtgatggcc
1701 ccgtggtatt gggtagaaag ttctgctttg ttctgtgatt acgcgccatt
1751 tcgatcaccg atatcatccg caggctatgg ccctcaatgt gtctatggtg
1801 caaggctggt acttgctgct acgaactcgc tagagtttac aggtgaacca
1851 ggtgattatt ctgcataccg ttttgagtgg acaacaatgc gccacaaccc
1901 attatttaac atccttaaca aacgtgttgg tgatggtctt gccaatgttg
1951 atttcaggtt acgccccttc aatgaatggt tgttggaggg tcaaccaagt
2001 cgtcggagtt gtaactcagc tggccacggc acgcccacgg ccacatgttc
2051 tcacaaaacc ccaaaccacg acacgctaga tgagtacatc tggggcagta
2101 cgtcatgtga cctgtttcac ccggcggagt tgacttctta cacaaccgtg
2151 tgcgtcagat tccgcaacta cctatcgggt gctgacggtg atgttagaat
2201 actgaatacg ccgactaggg aagtaatcga gggaaacgtg gtcacaagat
2251 gtgacgggat aagatgtctg gacagtaata aacgaataca gcatgtccct
2301 gaagtggcaa ggcgctactg catgatggcg cggtacctcg cacaagcccg
2351 tacttttgga gcactaacta ttggggatga tattatacgt ggttttgaca
2401 aggttgaaaa aatcgtcaaa atgcataaga gtaataatag attggatcaa
2451 atgcctttaa ttgatgttac tggattatgt cagccaatga ttgaaacaag
2501 tacagtgcgc gcctcaacac cgacgcgtat tgatcctaac aaacttgcgg
2551 ctgctacggc ccgggttgag ttaccactag ccccacgttg tacatcttct
2601 ttaatcccat catctgatac agtacccgaa ccagagcctc aagttggcga
2651 aaccggtgac aacggaggct gcgcttgatt gttttgaaaa tgtgcgacgt
2701 atgattagtg gtttcttgaa tctgtcgtgg ctgacagtaa catctaaaga
2751 aaggcaacat aaaagtgaca gtaattattt ctatgattat aatctcttct
2801 tttcccagat gccagcgata gttttcaacc aactaaaatg ctgtgtaaag
2851 acacaagttg acgatgccat aaaaactatt ttgcaaaaaa cgaagaaagt
2901 tgaacctagt aaacaggttg aaagaacgct cactctctcc gtgctaaaca
2951 cgttcctggg gtacctggac ttgggtaggt atgtaacaca atacacagag
3001 cagcagtcag ggccagttgc ggcaaaactg ctcttgacac tcctctcgtc
3051 agcgctaatt gcattggtcc ctgcgaaatc agaccccaat ttatgtcaga
3101 ataagatacc acgccattat tatcagctta aggcgcatgt tggggctcag
3151 aaaaaagtaa acttaacggc aatcgaggtg atcaggggtt gccaacacga
3201 gtgcagtgtc gtttattgtg agtatatgcg ttacagtgct tacttttcgg
3251 gcctgtatga tgatcaggtc gctgccatcc tgttatatgc tacggcagca
3301 cacggtgtcc aaggatttgg ggctcgattt agtattctgt gggcgcttac
3351 gtgcgttaag gcacctgatt ttgcggacga aattaatatt tatatcaagc
3401 acagaggtat gtcaggacta ctacctcagc tagtagagat gaaatgcttg
3451 ctaggtcgtg gggtgagtga gattgatgtc gaacttgagg ctagaaacag
3501 actaaacgta aagaacctga atatgcagaa gttcaacgaa gacgaactac
3551 gagcagccgt tcgtcaagtt tactctgaag aaatcaggag gtctgtttcg
3601 tacccgccga tttgtgattt ctggtcgtca cgttggctgt gggctgcaaa
3651 tggctcgcac tcccgcgctc tggaacatgc acatcctgag cttgcaacta
3701 ggaaagaagg gcaggcctac agaaaagcgg taatggaaca gtggcagcat
3751 aatcccatgg accgctggga tggcacagtg tatgtcaccc ctagtgctaa
3801 gcttgagcat ggaaagacaa gactactgtt ggcatgtgac acactgtcgt
3851 atatgtggtt tgaatatgcc ttacgacccg ttgaaaggat ctgggagaac
3901 agtaatgtca tccttgaccc tgggagtatc ggcaactgcg gtattgcagc
3951 cagagttaat aagtggcgaa acagtgttcg tggacagagc ttctttgcgg
4001 tagattatga tgacttcaat tctcaacata cgttgctgtc acagaagatt
4051 gtgtttgagg aattgtttca gcatatcaac tgcaatatgt cctggacccg
4101 aacattaata gattcttttg acagcatgga gttatgggtt aaagggaaaa
4151 gagctggtgt ggtggcaggg acgctgatga gcggtcatag agctaccagc
4201 ttcataaact ctgttctcga cagggcatac attatatgtg caggcggcca
4251 cgtacccacg tctatgcatg ttggtgatga catcttgatg tcatgtacat
4301 ttgaccatgc cgataatcta atagctaatc ttacggagaa tgggattagg
4351 ttaaatgcta gtaaacaagt ctttagtaaa actagtgggg agttcctacg
4401 agtggcacac cgtgaacaca caagccacgg gtatcttgcg agagtagtga
4451 gcagtgcggt atcggggaat tgggtgagtg atcacaccct caatcagcaa
4501 gaggccctca tgaatgctac agtatgttgc agaggaatcc tcaataggag
4551 cttaccaggt gacaagaatc ctgtggtcag ggtaatatca cgcagtgtaa
4601 gcaagagaac taaagtagat gaacgaataa ttcggctgtt actgagtggg
4651 aaagcgtgtc ttagaggtgg tgtcgtgtac ggtgaacaaa ctaactgcat
4701 ccaagtatat aagataaatt gcagggttga gcgcctagag gagaagctac
4751 ccccatacaa acatgcaact gaagattact tgaacaatca tctgacaggt
4801 attgaagtaa tggcagtcag acaatatgga tcggacattg ctgatatcat
4851 ggcccaggct agctggaaga aatccatgag taatgagagt gccgaagaaa
4901 tatctcgtct gtcactgtca cgcgacaaaa acctgccatg cctgtattgt
4951 atcacagagg atgaggttgc aacactgccg gttcgctacg ggttgttcac
5001 gagctatcca atcctaatga tgttgaagga taggatgccc atcaaagaag
5051 ccctcaaact agccataact gtaggttaca gaccccaacc taacagcgac
5101 atagagctag atttgtgggg tgagagcaaa aattcatgtg caattgaagg
5151 aatacttcct tataatgaag cgacttcaat ggcccaaaaa cttccttgtg
5201 gtggagttgt tatacaagta atacataatg tatatgtata aggacgcacc
5251 attcggaata tggcaagagt gccataaact atc