Sequence of DPV Saccharomyces cerevisiae Ty2 virus
Yeast transposon Ty1-17 and flanking tRNA-Glu 3/Leu 3,LEU2 genes from small ring of chromosome III (LEU2 coding for beta-isopropylmalate dehydrogenase)
ACC No: X03840
Dated: 2004-09-09 | Length: 11220 | CRC: -1175550539
!!NA_SEQUENCE 1.0
ID SCTY117X standard; genomic DNA; FUN; 11220 BP.
XX
AC X03840; J01333; K00633; M19542; X02991;
XX
SV X03840.1
XX
DT 18-NOV-1986 (Rel. 10, Created)
DT 09-SEP-2004 (Rel. 81, Last updated, Version 26)
XX
DE Yeast transposon Ty1-17 and flanking tRNA-Glu 3/Leu 3,LEU2 genes from small
DE ring of chromosome III (LEU2 coding for beta-isopropylmalate dehydrogenase)
XX
KW 3-isopropylmalate dehydrogenase; dehydrogenase;
KW isopropylmalate dehydrogenase; transfer RNA-Glu; transfer RNA-Leu;
KW transposon; Ty1 transposon.
XX
OS Saccharomyces cerevisiae (baker's yeast)
OC Eukaryota; Fungi; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
XX
RN [1]
RP 1-11220
RX MEDLINE; 86205247.
RX PUBMED; 3010239.
RA Warmington J.R., Anwar R., Newlon C.S., Waring R.B., Davies R.W.,
RA Indge K.J., Oliver S.G.;
RT "A 'hot-spot' for Ty transposition on the left arm of yeast chromosome
RT III";
RL Nucleic Acids Res. 14(8):3475-3485(1986).
XX
RN [2]
RP 9294-9945
RX DOI; 10.1016/0092-8674(82)90125-8.
RX MEDLINE; 83129346.
RX PUBMED; 6297759.
RA Andreadis A., Hsu Y.P., Kohlhaw G.B., Schimmel P.;
RT "Nucleotide sequence of yeast LEU2 shows 5'-noncoding region has sequences
RT cognate to leucine";
RL Cell 31(2 Pt 1):319-325(1982).
XX
RN [3]
RP 9911-9954
RX MEDLINE; 84032259.
RX PUBMED; 6313610.
RA Erhart E., Hollenberg C.P.;
RT "the presence of a defective leu2 gene on 2 micron dna recombinant plasmids
RT of saccharomyces cerevisiae is responsible for curing and high copy
RT number";
RL J. Bacteriol. 156(2):625-635(1983).
XX
RN [4]
RP 3427-9388
RX MEDLINE; 86041864.
RX PUBMED; 2997719.
RA Warmington J.R., Waring R.B., Newlon C.S., Indge K.J., Oliver S.G.;
RT "Nucleotide sequence characterization of Ty 1-17, a class II transposon
RT from yeast";
RL Nucleic Acids Res. 13(18):6679-6693(1985).
XX
RN [5]
RP 3427-4639
RX MEDLINE; 88295213.
RX PUBMED; 2841030.
RA Warmington J.R., Oliver S.G.;
RT "A downstream activator sequence regulates the expression of the yeast
RT transposon";
RL Curr. Genet. 13(5):357-362(1988).
XX
DR TRANSFAC; R00969; Y$LEU2_01.
DR TRANSFAC; R00970; Y$LEU2_02.
DR TRANSFAC; R03163; Y$LEU2_03.
XX
FH Key Location/Qualifiers
FH
FT source 1. .11220
FT /db_xref="taxon:4932"
FT /mol_type="genomic DNA"
FT /organism="Saccharomyces cerevisiae"
FT tRNA 1428. .1499
FT /note="tRNA-Glu"
FT misc_feature 1575. .1590
FT /note="delta insert"
FT misc_feature 1627. .1636
FT /note="delta insert"
FT repeat_region complement(1680. .1818)
FT /note="repeat delta sequence"
FT repeat_region 1819. .1878
FT /note="repeat delta sequence"
FT repeat_region 2680. .2685
FT /note="direct repeat 1"
FT repeat_region 2685. .2910
FT /note="repeat delta A sequence"
FT repeat_region 2906. .2910
FT /note="direct repeat 2"
FT repeat_region 2911. .3243
FT /note="repeat delta B sequence"
FT repeat_region 3244. .3378
FT /note="repeat delta A sequence"
FT repeat_region 3244. .3248
FT /note="direct repeat 2"
FT repeat_region 3378. .3382
FT /note="direct repeat 1"
FT repeat_region 3427. .9388
FT /transposon="Ty 1-17"
FT repeat_region 3427. .3758
FT /note="direct repeat, delta sequence [4]"
FT TATA_signal 3593. .3599
FT /note="put. TATA-box [4]"
FT RBS 3667. .3671
FT /note="put. rRNA binding site [4]"
FT CDS 3718. .5034
FT /db_xref="GOA:P25383"
FT /db_xref="UniProt/Swiss-Prot:P25383"
FT /note="TYA (aa 1-438) [4]"
FT /protein_id="CAA27457.1"
FT /translation="MESQQLHQNPRSLHGSAYASVTSKEVPSNQDPLAVSASNLPEFDR
FT DSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHY
FT QQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQNQHSEVPQAETKVRN
FT NVLPPHTLTSDENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQA
FT FAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGSTSADT
FT FEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQ
FT LIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYQRTNSSKPRAAKAHNI
FT ATSSKFSRVNNDHINESTVSSQYLSDDNELSLRPATERI"
FT misc_feature 3759. .9056
FT /note="epsilon sequence [4]"
FT misc_feature 3759. .3782
FT /note="sequence homologous to yeast tRNA-Met [4]"
FT repeat_unit 3819. .3832
FT /note="inverted repeat A [4]"
FT misc_feature 4012. .4041
FT /note="DAS (homology to SV40 enhancer core) [5]"
FT misc_feature 4042. .4066
FT /note="DAS (homology to diploid-regulation- site of yeast
FT MAT gene) [5]"
FT misc_feature 4075. .4092
FT /note="put. regulatory region; sequence homologous to
FT diploid control site [4]"
FT misc_feature 4080. .4106
FT /note="DAS (homology to SV40 enhancer core and to
FT diploid-regulation-site of yeast MAT gene) [5]"
FT misc_signal 4215. .4229
FT /note="enhancer-like element [4]"
FT misc_feature 4234. .4262
FT /note="DAS (homology to SV40 enhancer core and to
FT diploid-regulation-site of yeast MAT gene) [5]"
FT misc_feature 4241. .4258
FT /note="put. regulatory region; sequence homologous to
FT diploid control site [4]"
FT CDS 4991. .9034
FT /db_xref="GOA:P25384"
FT /db_xref="UniProt/Swiss-Prot:P25384"
FT /note="TYB (first ATG pos.) [4]"
FT /protein_id="CAA27458.1"
FT /translation="MTTNLVLGQQQKESKPTHTIDSNDELPDHLLIDSGRSQTLVRSAH
FT YLHHATPNSEINIVDAQKQDIPINAIGNLHFNFQNGTKTSIKALHTPNIAYDLLSLSEL
FT ANQNITACFTRNTLERSDGTVLAPIVKHGDFYWLSKKYLIPSHISKLTINNVNKSKSVN
FT KYPYPLIHRMLGHANFRSIQKSLKKNAVTYLKESDIEWSNACTYQCPDCLIGKSTKHRH
FT VKGSRLKYQESYEPFQYLHTDIFGPVHHLPKSAPSYFISFTDEKTRFQWVYPLHDRREE
FT SILNVFTSILAFIKNQFNARVLVIQMDRGSEYTNKTLHKFFTNRGITACYTTTADSRAH
FT GVAERLNRTLLNDCRTLLHCSGLPNHLWFSAVEFSTIIRNSLVSPKNDKSAARQHAGLA
FT GLDITTILPFGQPVIVNNHNPDSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTN
FT YVILQDKQSKLDQFNYDTLTFDDDLNRLTAHNQSFIEQNETEQSYDQNTESDHDYQSEI
FT EINSDPLVNDFSSQSINPLQLDKEPVQKVRAPKEVDADISEYNILPSPVRSRTPHIINK
FT ESTEMGGTVESDTTSPRHSSTFTARNQKRPGSPNDMIDLTSQDRVNYGLENIKTTRLGG
FT TEEPYIQRNSDTNIKYRTTNSTPSIDDRSSNSESTTPIISIETKAVCDNTPSIDTDPPE
FT YRSSDHATPNIMPDKSSKNVTADSILDDLPLPDLTHQSPTDTSDVSKDIPHIHSRQTNS
FT SLGGMDDSNVLTTTKSKKRSLEDNETEIEVSRDTWNNKNMRSLEPPRSKKRINLIAAIK
FT GVKSIKPVRTTLRYDEAITYNKDNKEKDRYVEAYHKEISQLLKMNTWDTNKYYDRNDID
FT PKKVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSDMQSNTVHHYALMTSLSIALDN
FT DYYITQLDISSAYLYADIKEELYIRPPPHLGLNDKLLRLRKSLYGLKQSGANWYETIKS
FT YLINCCDMQEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIIN
FT LGESDNEIQYDILGLEIKYQRSKYMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGH
FT YIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLLNHILFPSRQVLD
FT MTYELIQFMWDTRDKQLIWHKNKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKV
FT IGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISI
FT IKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTN
FT KWIH"
FT repeat_region 9057. .9388
FT /note="direct repeat, delta sequence [4]"
FT repeat_unit 9170. .9183
FT /note="inverted repeat A' [4]"
FT misc_signal 9309. .9312
FT /note="5' end of put. transcript termination signal [4]"
FT conflict 9318
FT /replace="c"
FT /citation=[2]
FT /citation=[3]
FT misc_feature 9357. .9362
FT /note="transcription termination region [4]"
FT tRNA 9478. .9594
FT /note="tRNA-Leu-3"
FT conflict 9917. .9918
FT /replace=""
FT /citation=[2]
FT /citation=[3]
FT CDS 9943. .11037
FT /db_xref="GOA:P04173"
FT /db_xref="HSSP:P12010"
FT /db_xref="SGD:S000000523"
FT /db_xref="UniProt/Swiss-Prot:P04173"
FT /product="beta-isopropylmalate dehydrogenase"
FT /gene="LEU 2"
FT /protein_id="CAA27459.1"
FT /translation="MSAPKKIVVLPGDHVGQEITAEAIKVLKAISDVRSNVKFDFENHL
FT IGGAAIDATGVPLPDEALEASKKVDAVLLGAVGGPKWGTGSVRPEQGLLKIRKELQLYA
FT NLRPCNFASDSLLDLSPIKPQFAKGTDFVVVRELVGGIYFGKRKEDDGDGVAWDSEQYT
FT VPEVQRITRMAAFMALQHEPPLPIWSLDKANVLASSRLWRKTVEETIKNEFPTLKVQHQ
FT LIDSAAMILVKNPTHLNGIIITSNMFGDIISDEASVIPGSLGLLPSASLASLPDKNTAF
FT GLYEPCHGSAPDLPKNKVNPIATILSAAMMLKLSLNLPEEGKAIEDAVKKVLDAGIRTG
FT DLGGSNSTTEVGDAVAEEVKKILA"
FT conflict 9950
FT /replace="g"
FT /citation=[3]
XX
SQ Sequence 11220 BP; 3998 A; 2177 C; 1933 G; 3112 T; 0 other;
X03840 Length: 11220 May 9, 2005 17:26 Type: N Check: 7812 ..
1 ggatcccgga ttaacgcctg ttactgagac acttcctaac aacctaaaag
51 aaaaaacagc tctgctgcag gatactgaaa agaaaataat agaaacgata
101 cgcagatcca aatttttagg atcgctacta aatgttagag ggggactatc
151 gccagggaaa agtgaactgg cacctatcga agagtctccc atagtttcaa
201 ccacaccact aatatataat gatcgaatgg aacctcgtag gatatccgat
251 gtggaagtcc cacatttcac gaggaaatca aaacacttta ctactgctaa
301 taatcggcgc tcagtcttat ctttgtatgc gaaggattca atcaaagact
351 taaacgaatt tttaataaag gaagatcctg atttgcctcc acaaggaagc
401 actgataacg aaagtaggag cgaagatccc gaaatagccg agagtatcac
451 tgattcaagg aatatacaat atgatgagga tgatagtaag gatggtgata
501 atgtgaataa tgataatata ttgagcgact ttccctcaag gcgttggcat
551 atcacaggaa tacgacatga aggataaaaa tccaaaccaa tctccaatat
601 caaaaagcgc agagcccaca ctggtagtga aacttccgtc tttgagttct
651 ttccaaggaa aaaacgccag tgggttgggc ctataccaaa gagagccttc
701 taaggtaacc ttaccgagcc ttacaagtaa taacagcagc gtcggagaaa
751 acactagagg atggggcgga aaaagggact gagagtgaga aaatcgctgc
801 ttccctgtca gacgatgact tgaaggaaga taatgacaag aaagataacg
851 acacagtgaa tgccctacta cagtaaaaaa gccacctaac agcgtactct
901 tgaaaaaatt ctcaaaaggt aaaatcttag aacttgaaat acatgccaaa
951 atacctgaaa agagactata cgagggccta cataaactac tagaaggctg
1001 gaagcaatac gggttgaaaa acctggtgtt taacatcact aatatgatca
1051 taacaggaaa attggtgaat gacagtattt tatttttacg atctacgctt
1101 tttgaaataa tggttttacc aaatggagac ggtagaagtt taattaaatt
1151 caataagaaa acaggatcta ctaaaacgct gaccaagctt gctacagaaa
1201 tccaaattat tttacaaaaa gaaggtgttt tggacaaata aaaaaaaggg
1251 agggataatc tatccccaaa tggacaatac gatgtaacac cgttatataa
1301 ttaataaatg tatatatgta actatttttt gaaaaaaata aaatggtaat
1351 ttattaaata tttggaccgg tcaacaatct cagatatagt tgaaaaaatc
1401 tttaattgta atagcagaaa aaaaaaactc cgatacgggg agtcgaaccc
1451 cggtctccac ggtgaaagcg tgatgtgata gccgttacac tatatcggat
1501 aacaaattat taaaattatt taataaaaag atgaactaat ggtgtataaa
1551 aacatcataa aaactcaact caactgttcc aataaaatct gcaatttaaa
1601 ttaattattc tgaaaaaaca cgtaaattgt tggaatggaa ccctaaaata
1651 tttcctcttt agtactattc atgttacttg agaaatgggt gaattttgag
1701 atagttgttg ggattccatt gttgataaag gctaataata ttaggtatac
1751 agaatatgct agaggttctc ctcgagcata taggaatcct caaaatggaa
1801 ttagcatttc tacataataa cctcaattcc cttttgtgga ttcacatatt
1851 ctcgatcgga actcctagca tagtgcagac aacactcaca tagctctccc
1901 atttatcaag ttggaattca ctccaagaaa ttttcttgct tctctctttc
1951 ccacagaaat gaaaaggaac agtttggcgg ctattgtttt agcccttact
2001 ttttggaccc tttgaaaaaa tgccaagaat gcgtgacggt ttccctccat
2051 gctcgagaac cacaaaaacc ctatgtggta ttcgattatg cgactcacgg
2101 caaatatttg acttgtcaaa gttattcggg atttccttga atccctgaga
2151 agtgaaatgg aaagaattta agggcataaa tacctttcaa gcacccagaa
2201 gaacagtaaa ataaagcaag gtacgtgaaa ttaatatttt taaatggttc
2251 taaccgatgc cgaagaactg cgcgatccgg ttataacgtc tgacatgtcc
2301 ttttttgatt tggaatccaa ccactcagtg actctgtcat tacttgcgaa
2351 attattccac aaattccatc gaaagtgaat cgcaaaccac cttcagactg
2401 gcaccgacaa agcaaagatt atacagacag agtactttat acgtaccgtt
2451 aagtctcaag caaagggttt tcttatttac tgaacgggta aagagtatct
2501 gggccggctt gccaagatgc aaaccgaata agtatttcaa agttgcattt
2551 gccttagccg tcctgacacc attggctatt tggatatttt atattgactt
2601 tcgtgtacat tgatcacatc gactgttcta ttggcaaatg aaccacgggc
2651 attgactatt tttcaggtta ctactatata ttattgttgg aataaaaatc
2701 aactatcatc tactaactag tatttacgtt actagtatat tatcatatac
2751 ggtgttagaa gatgacgcaa atgatgagaa atagtcatct aaattagtgg
2801 aagctgaaac acaaggattg ataatgtaat aggatcaatg aatattaaca
2851 tataaaatga tgataataat atttatagaa ttgtgtagaa ttgcagattc
2901 ccttttatgg tgttggaata aaaatcaact atcatctact aactagtatt
2951 tacgttacct agtatattat catatacggt gttagaagat gacgcaaatg
3001 atgagaaata gtcatctaaa ttagtggaag ctgaaacgca aggattgata
3051 atgtaatagg atcaatgaat attaacatat aaaatgatga taataatatt
3101 tatagaattg tgtagaattg cagattccct tttatggatt cctaaatcct
3151 cgaggagaac ttctagtata tctacatacc taatattatt gccttataaa
3201 aaatggaatc ccaacaatta catcaaaatc cacgttcttt tcatatggat
3251 tcctaaatcc tcgaggagaa tttataatat agtctgtata cataatatta
3301 tagcttctaa cgacaatgga attctaacaa ttatcaaatt gccgccagtt
3351 cctcaaaaag atccatgtat aatcttcatt attacagccc tcttgacctc
3401 taatcatgaa tgttctcaaa taaatctgtt ggaataaaaa tcaactatca
3451 tctactaact agtatttacg ttactagtat attatcatat acggtgttag
3501 aagatgacgc aaatgatgag aaatagtcat ctaaattagt ggaagctgaa
3551 acgcaaggat tgataatgta ataggatcaa tgaatattaa catataaaat
3601 gatgataata atatttatag aattgtgtag aattgcagat tcccttttat
3651 ggattcctaa atcctcgagg agaacttcta gtatatctac atacctaata
3701 ttattgcctt ataaaaaatg gaatcccaac aattacatca aaatccacgt
3751 tctcttcatg gtagcgccta tgcttcggtt acttctaagg aagtcccatc
3801 aaatcaagat ccgttagccg tttcagcttc caatttaccg gaatttgata
3851 gagattccac taaggttaat tctcaacaag agacaacacc tgggacatca
3901 gctgttccag agaaccatca tcatgtctct cctcaacctg cttcagtacc
3951 acctccacag aatggacagt accaacagca cggcatgatg accccaaaca
4001 aagctatggc ctctaactgg gcacattacc aacaaccgtc tatgatgacg
4051 tgttcacatt atcaaacgtc acctgcgtat tatcaaccgg acccacacta
4101 tccgttgcca cagtatatcc caccactgag tacttcctca cctgatccaa
4151 tcgattcaca gaatcaacac tctgaagtac ctcaagctga gacaaaggtg
4201 agaaataacg tcttaccacc acacacttta acatcagatg aaaacttttc
4251 tacatgggtt aaattttaca tcagattttt gaagaactct aatctcggtg
4301 acatcattcc aaatgaccag ggtgaaatca aaagacaaat gacttatgaa
4351 gaacatgcgt atatatacaa taccttccaa gcatttgccc catttcattt
4401 attgccaaca tgggtaaaac aaattttaga aattaattat gctgacatcc
4451 ttacagtcct ttgtaaaagt gtgtccaaaa tgcaaactaa caatcaagaa
4501 ttaaaggatt ggatagctct tgccaacctt gagtacgacg gaagtacatc
4551 tgctgataca tttgaaatta cagtcagtac gatcattcag aggctaaaag
4601 aaaacaatat caatgttagc gacagattgg cctgtcaact aatacttaaa
4651 ggtctatccg gtgacttcaa atacctacgt aatcaatatc gtaccaaaac
4701 gaacatgaaa ctttcccaat tattcgctga aattcagtta atatatgacg
4751 aaaataaaat catgaatcta aataaaccgt cccaatacaa acaacacagc
4801 gaatacaaaa atgtttctcg cacatctcca aacacgacta acacaaaggt
4851 tacaactcgt aattatcaga gaacaaatag ttcaaaacca agagcagcaa
4901 aagctcacaa tattgctaca tctagtaaat tctcaagggt gaacaatgat
4951 cacattaatg aatcaaccgt ttcatcacaa tacttaagcg atgacaacga
5001 acttagtctt aggccagcaa cagaaagaat ctaagccaac acacacaata
5051 gactcgaatg acgaactacc tgatcacctt cttattgatt caggacgttc
5101 gcaaacgctt gtcagatcag cccattattt acaccatgca acacccaatt
5151 ctgaaataaa catagtcgat gctcaaaaac aagacattcc tataaatgcc
5201 attggtaatc ttcacttcaa ctttcagaac ggcaccaaaa catcaataaa
5251 agcactacac acaccaaaca tagcctatga tctattaagt ttgagtgagc
5301 tggctaatca aaatattaca gcctgcttta ccagaaacac tttagaaaga
5351 tcggatggta cagtcctagc tcccatagtc aaacatggag acttttactg
5401 gttatctaaa aaatacctaa ttccttcgca catttcaaag ctaacaataa
5451 acaacgtcaa caaaagcaaa agcgtaaata aatatccata tccgttaata
5501 catcgaatgc ttggacatgc taacttccga agtattcaga agtctcttaa
5551 gaagaatgca gttacatatt tgaaggaatc ggatattgaa tggtctaacg
5601 catgcacata tcaatgtcct gactgtctaa tcggcaaaag cacgaaacat
5651 agacatgtca aaggatcacg actaaagtac caagaatcat atgagccttt
5701 tcagtacttg cataccgata tatttggtcc tgtacatcac ttaccgaaaa
5751 gtgcaccttc ttactttata tcgtttacag atgagaaaac cagattccaa
5801 tgggtgtacc cattacacga ccgtcgtgaa gaatctatcc tcaatgtttt
5851 tacatcgata ttagcattta ttaagaacca attcaatgct cgcgttctag
5901 ttatccagat ggatcgtggc tccgagtaca ctaacaaaac tcttcataag
5951 ttctttacga acagaggtat tactgcatgc tatacaacca cggcagattc
6001 tagagcacac ggtgtcgctg aacgattaaa tcgtacttta ttaaacgatt
6051 gtcgcacact gcttcattgc agtggtctac caaatcatct atggttctca
6101 gcagtcgaat tttctactat aatcagaaat tcattagtct caccaaaaaa
6151 cgataaatcc gccgcaagac aacatgcagg tttagctgga ctggacatta
6201 ctactatact acctttcggt caaccggtta tagttaacaa ccataatccc
6251 gactcgaaaa tacatcctcg tggcattcca ggttacgcct tacatccgtc
6301 acgaaactct tatggctata ttatctatct tccatcatta aaaaagacag
6351 tagatactac caattacgtt atattacaag acaagcaatc caaattggac
6401 caattcaatt atgatacact cacctttgat gatgatctca atcgtttaac
6451 agcccataac caatctttta ttgaacaaaa tgaaacggag cagtcatatg
6501 atcaaaatac agaatctgat catgactatc aatcggagat tgaaataaac
6551 tctgatcctc tagtgaacga cttctcgtcc caatcaataa accctttaca
6601 attagacaag gaaccagtcc aaaaagtacg tgcaccaaaa gaagttgatg
6651 ccgacatatc tgaatacaat attcttccat ctcctgtacg atctcgtaca
6701 ccccatatca ttaataaaga gagtaccgaa atgggtggta ccgttgaatc
6751 agatactact tcacctagac actcgtctac cttcactgca cgaaaccaaa
6801 agcgacctgg tagtcccaat gatatgattg atttgacctc acaggataga
6851 gttaattatg gacttgaaaa catcaaaact acacgtttgg gtggtacgga
6901 ggaaccatat attcaacgaa atagtgatac aaatatcaaa tacaggacta
6951 caaatagtac gccctcaata gatgaccgtt cgtccaacag tgaatccact
7001 actcccatca tctccataga aacaaaggct gtatgtgata atacaccctc
7051 cattgatacg gatccgccag aatatcgatc ttctgaccat gcgactccta
7101 atataatgcc tgacaaatcc tcaaaaaatg ttacggctga ttctattctt
7151 gacgacctcc cacttcctga cttaacccat caatctccta cggacacttc
7201 tgatgtttca aaagatattc cacacataca ctctcgtcag actaattcca
7251 gtttgggtgg tatggatgat tctaatgttc tgactactac caaaagtaag
7301 aaaagatcat tagaagataa tgaaactgaa attgaggtat cccgagacac
7351 atggaataat aagaatatga gaagtctgga accaccaaga tcgaagaaac
7401 gcataaattt aattgcagca ataaaaggag tgaaatcgat caaaccagtt
7451 cgaacgacct taagatatga tgaagcaatt acttataata aagacaacaa
7501 agaaaaagac agatatgttg aagcttatca taaagaaatt agccaactat
7551 tgaaaatgaa cacttgggat acaaacaaat attatgatag aaatgacata
7601 gatcctaaaa aagtaataaa ctcaatgttt atatttaaca agaaacgtga
7651 tggtacacac aaagctagat ttgttgcaag aggcgacatt caacaccccg
7701 atacatatga ttctgatatg caatccaata ccgtacatca ctatgcactg
7751 atgacgtcac tgtcaatcgc attagacaac gactattata tcacacagct
7801 ggacatatcc tctgcttact tatatgctga tatcaaagaa gaattataca
7851 taagacctcc accacattta ggtttgaatg ataaattact acgtttgaga
7901 aaatcactct atggtttgaa acaaagtggt gcaaactggt atgaaaccat
7951 taaatcatat ttaataaatt gttgcgacat gcaagaagtt cgcggatggt
8001 catgcgtatt taagaatagt caagtaacaa tttgcttatt cgttgatgat
8051 atgatattat tcagcaaaga cttaaatgca aataagaaaa tcataacaac
8101 actcaagaaa caatacgata caaagataat aaatctgggt gaaagtgata
8151 acgaaattca gtacgacata cttggattag agatcaaata tcaaagaagc
8201 aagtacatga aattaggtat ggaaaaatcc ttgacagaaa aattacccaa
8251 actaaacgta cctttgaacc caaaaggaaa gaaacttaga gctccaggtc
8301 aaccaggtca ttatatagac caggatgaac tagaaataga tgaagatgaa
8351 tacaaagaga aagtacatga aatgcaaaag ttgattggtc tagcttcata
8401 tgttggatat aaatttagat ttgacttact atactacatc aacacattgc
8451 tcaaccatat actattcccc tctaggcaag ttttagacat gacatatgag
8501 ttaatacaat tcatgtggga cactagagat aaacaattaa tatggcacaa
8551 aaacaaacct accaagccag ataataaact agtcgcaata agcgatgctt
8601 catatggtaa ccaaccatat tacaagtcac aaattggtaa cattttccta
8651 ctcaacggaa aagtgattgg aggaaagtcg acaaaggctt cgttaacatg
8701 cacttcaact acagaagcag aaatacacgc ggtcagtgaa gctattccgc
8751 tattgaataa cctcagtcac cttgtgcaag aacttaacaa gaaaccaatt
8801 attaaaggct tacttactga tagtagatca acgatcagta taattaagtc
8851 tacaaatgaa gagaaattta gaaacagatt ttttggcaca aaggcaatga
8901 gacttagaga tgaagtatca ggtaataatt tatacgtata ctacatcgag
8951 accaagaaga acattgctga tgtgatgaca aaacctcttc cgataaaaac
9001 atttaaacta ttaactaaca aatggattca ttagatctat tacattatgg
9051 gtggtatgtt ggaataaaaa tcaactatca tctactaact agtatttacg
9101 ttactagtat attatcatat acggtgttag aagatgacgc aaatgatgag
9151 aaatagtcat ctaaattagt ggaagctgaa acgcaaggat tgataatgta
9201 ataggatcaa tgaatattaa catataaaat gatgataata atatttatag
9251 aattgtgtag aattgcagat tcccttttat ggattcctaa atcctcgagg
9301 agaacttcta gtatatctac atacctaata ttattgcctt attaaaaatg
9351 gaatcccaac aattacatca aaatccacat tctcttcaaa atcaattgtc
9401 ctgtacttcc ttgttcatgt gtgttcaaaa acgttatatt tataggataa
9451 ttatactcta tttctcaaca agtaattggt tgtttggccg agcggtctaa
9501 ggcgcctgat tcaagaaata tcttgaccgc agttaactgt gggaatactc
9551 aggtatcgta agatgcaaga gttcgaatct cttagcaacc attatttttt
9601 tcctcaacat aacgagaaca cacaggggcg ctatcgcaca gaatcaaatt
9651 cgatgactgg aaattttttg ttaatttcag aggtcgcctg acgcatatac
9701 ctttttcaac tgaaaaattg ggagaaaaag gaaaggtgag agccgcggaa
9751 ccggcttttc atatagaata gagaagcgtt catgactaaa tgcttgcatc
9801 acaatacttg aagttgacaa tattatttaa ggacctattg ttttttccaa
9851 taggtggtta gcaatcgtct tactttctaa cttttcttac cttttacatt
9901 tcagcaatat atatatatat atttcaagga tataccattc taatgtctgc
9951 ccctaagaag atcgtcgttt tgccaggtga ccacgttggt caagaaatca
10001 cagccgaagc cattaaggtt cttaaagcta tttctgatgt tcgttccaat
10051 gtcaagttcg atttcgaaaa tcatttaatt ggtggtgctg ctatcgatgc
10101 tacaggtgtc ccacttccag atgaggcgct ggaagcctcc aagaaggttg
10151 atgccgtttt gttaggtgct gtgggtggtc ctaaatgggg taccggtagt
10201 gttagacctg aacaaggttt actaaaaatc cgtaaagaac ttcaattgta
10251 cgccaactta agaccatgta actttgcatc cgactctctt ttagacttat
10301 ctccaatcaa gccacaattt gctaaaggta ctgacttcgt tgttgtcaga
10351 gaattagtgg gaggtattta ctttggtaag agaaaggaag acgatggtga
10401 tggtgtcgct tgggatagtg aacaatacac cgttccagaa gtgcaaagaa
10451 tcacaagaat ggccgctttc atggccctac aacatgagcc accattgcct
10501 atttggtcct tggataaagc taatgttttg gcctcttcaa gattatggag
10551 aaaaactgtg gaggaaacca tcaagaacga attccctaca ttgaaggttc
10601 aacatcaatt gattgattct gccgccatga tcctagttaa gaacccaacc
10651 cacctaaatg gtattataat caccagcaac atgtttggtg atatcatctc
10701 cgatgaagcc tccgttatcc caggttcctt gggtttgttg ccatctgcgt
10751 ccttggcctc tttgccagac aagaacaccg catttggttt gtacgaacca
10801 tgccacggtt ctgctccaga tttgccaaag aataaggtca accctatcgc
10851 cactatcttg tctgctgcaa tgatgttgaa attgtcattg aacttgcctg
10901 aagaaggtaa ggccattgaa gatgcagtta aaaaggtttt ggatgcaggt
10951 atcagaactg gtgatttagg tggttccaac agtaccacgg aagtcggtga
11001 tgctgtcgcc gaagaagtta agaaaatcct tgcttaaaaa gattctcttt
11051 ttttatgata tttgtacata aactttataa atgaaattca taatagaaac
11101 gacacgaaat tacaaaatgg aatatgttca tagggtagac gaaactatat
11151 acgcaatcta catacattta tcaagaagga gaaaaaggag gatgtaaagg
11201 aatacaggta agcaaattga