Notes on Family: Bornaviridae
enveloped spheres
Contents
General Description
This family is characterised by its spherical, enveloped, particles of about 90 nm diameter, which contain a monopartite negative sense ssRNA genome. It is classified in the order
Mononegavirales with three other families of enveloped viruses with monopartite negative sense genomes, i.e. the
Filoviridae (particles usually filamentous),
Paramyxoviridae (particles >150 nm diameter) and
Rhabdoviridae (particles bullet-shaped).
Morphology
Virions isometric, enveloped, about 90 nm in diameter, with small (7 nm) projections.
Genomen
Monopartite single-stranded negative sense RNA of about 8.9 kb. There is no genome-linked protein (VPg) at the 5'-terminus nor a 3'-polyA tail. There are 6 major ORFs with the RNA polymerase at the 5'-end of the genome and the capsid nucleoprotein at the 3'-end.
Genera in the Family
There is currently only one genus:
