Notes on Genus: Dinovernavirus

icosahedra
icosahedra

Type member: Aedes pseudoscutellaris reovirus

Contents

General Description

This is one of the animal virus genera in the family Reoviridae. Members have 9 segments (fewer than any other genus in the family) and infect insects. The name reflects the fact that these are double-stranded, insect viruses with nine (latin novem), RNA segments.

Morphology

Virions isometric (icosahedral), 55-69 nm in diameter, with a single capsid shell and hollow surface spikes similar to those of the genus Cypovirus.

Genome

Linear, double stranded RNA in 9 segments. Five of these are larger than 3 kb in size. Each virion contains a single copy of the entire genome. Total genome c.23000 nucleotides long.

Genus Genomic Organization

Each segment has a single ORF.

Type Member Genomic Organization

  • Segment 1 (3817 nt) encodes the VP1 protein (134.7 kDa)
  • Segment 2 (3752 nt) encodes a putative viral polymerase VP2 (143.3 kDa)
  • Segment 3 (3732 nt) encodes the VP3 protein (136.3 kDa)
  • Segment 4 (3375 nt) encodes the VP4 protein (116.5 kDa)
  • Segment 5 (3227 nt) encodes the VP5 protein (121.2 kDa)
  • Segment 6 (1775 nt) encodes the VP6 protein (62.2 kDa)
  • Segment 7 (1171 nt) encodes the VP7 protein (39.4 kDa)
  • Segment 8 (1151 nt) encodes the VP8 protein (39.5 kDa)
  • Segment 9 (1147 nt) encodes the VP9 protein (32.2 kDa)