Notes on Genus: Dinovernavirus
icosahedra
Type member: Aedes pseudoscutellaris reovirus
Contents
General Description
This is one of the animal virus genera in the family
Reoviridae. Members have 9 segments (fewer than any other genus in the family) and infect insects. The name reflects the fact that these are
double-stranded,
insect viruses with nine (latin
novem),
RNA segments.
Morphology
Virions isometric (icosahedral), 55-69 nm in diameter, with a single capsid shell and hollow surface spikes similar to those of the genus
Cypovirus.
Genome
Linear, double stranded RNA in 9 segments. Five of these are larger than 3 kb in size. Each virion contains a single copy of the entire genome. Total genome
c.23000 nucleotides long.
Genus Genomic Organization
Each segment has a single ORF.
Type Member Genomic Organization
- Segment 1 (3817 nt) encodes the VP1 protein (134.7 kDa)
- Segment 2 (3752 nt) encodes a putative viral polymerase VP2 (143.3 kDa)
- Segment 3 (3732 nt) encodes the VP3 protein (136.3 kDa)
- Segment 4 (3375 nt) encodes the VP4 protein (116.5 kDa)
- Segment 5 (3227 nt) encodes the VP5 protein (121.2 kDa)
- Segment 6 (1775 nt) encodes the VP6 protein (62.2 kDa)
- Segment 7 (1171 nt) encodes the VP7 protein (39.4 kDa)
- Segment 8 (1151 nt) encodes the VP8 protein (39.5 kDa)
- Segment 9 (1147 nt) encodes the VP9 protein (32.2 kDa)