Notes on Genus: Giardiavirus


Type member: Giardia lamblia virus


General Description

This genus contains those members of the family Totiviridae that infect protozoa of the genus Giardia and which have particles 36nm in diameter. The name is derived from the genus infected by the type member.


Virions isometric, 36 nm in diameter.


Monopartite, linear, double stranded DNA of about 6300 base pairs.

Genus Genomic Organization

The genome has two large, overlapping ORFs on the positive strand that encode respectively the coat protein (gag) and polymerase (pol).

Type Member Genomic Organization

There are two large, overlapping ORFs on the positive strand:
1. 98 kDaCoat protein (gag)
2.   120 kDaPolymerase (pol): RNA-dependent RNA polymerase expressed as a fusion protein with gag by a -1 ribosomal frameshift