Notes on Genus: Iflavirus
Type member: Infectious flacherie virus
This genus (the sole member of the family Iflaviridae
), contains viruses of invertebrates that belong in the picornavirus "superfamily", and which share a number of features, both of virion structure and genomic organisation, of members of the families Picornaviridae
but which form a distinct group in phylogenetic analyses. It is named from the type member, I
Virions isometric (icosahedral), not enveloped 30 nm in diameter.
Monopartite, linear, positive sense single-stranded RNA of 8.5-10 kb. There is a genome-linked protein (VPg) at the 5'-terminus and a 3'-polyA tail.
Genus Genomic Organization
The RNA encodes a single polyprotein of 330-350 kDa that is subsequently processed into the functional products. The 3 (or sometimes 4) coat proteins are encoded near the N-terminus.
Type Member Genomic Organization
The RNA encodes a single polyprotein of 346 kDa that is subsequently processed into the functional products. The 3 coat proteins are encoded near the N-terminus and the non-structural proteins contain the recognised motifs for the RNA helicase, cysteine protease and the RNA polymerase.