Notes on Genus: Lolavirus

flexuous filaments
flexuous filaments

Type member: Lolium latent virus

Contents

General Description

The genus Lolavirus is one of the genera in the family Alphaflexiviridae. In genome organisation and phylogenetic analysis its single member particularly resembles viruses in the genus Potexvirus but the virions are longer, the coat protein is larger and there is probably a small additional ORF6. Its name is derived from the type species Lolium latent virus.

Morphology

Virions filamentous, not enveloped, c. 640 nm long and 13 nm in diameter.

Genome

Monopartite, linear, single stranded, positive-sense RNA, c. 7700 nucleotides long. The 3' terminus has a poly(A) tract.

Genus Genomic Organization

There are a 5, or more likely 6, open reading frames, probably translated by means of subgenomic RNAs.

Type Member Genomic Organization

There are 6 predicted open reading frames, probably translated by means of subgenomic RNAs:
1 196 kDa Polymerase
2 30 kDa ORFs 2-4 (Triple gene block):
translated from different reading frames
and all involved in cell-to-cell movement
3 13 kDa
4 7 kDa
5 32 kDaCoat protein
6 5 kDaProbable nucleic acid binding protein (NABP)