Notes on Genus: Quadrivirus
Type member: Rosellinia necatrix quadrivirus 1
The genus Quadrivirus
is the only genus in the family Quadriviridae
. It is named because the genome has four segments.
Virions isometric (icosahedral), not enveloped, about 48 nm in diameter.
Quadripartite, linear double-stranded RNA, with segments ranging in size from 3.7 to 4.9 kbp. A terminal sequence of seven 5â€™- and fourteen 3â€™-nucleotides is strictly conserved in all segments.
Genus Genomic Organization
There are four RNAs, each encoding a single protein.
Type Member Genomic Organization
- RNA1 (4.9 kbp) encodes a protein of 178 kDa (function unknown)
- RNA2 (4.4 kbp) encodes a stuctural protein of 147 kDa
- RNA3 (4.1 kbp) encodes a polymerase of 147 kDa
- RNA4 (3.7kbp) encodes a second structural protein of 113 kDa