Notes on Genus: Quadrivirus


Type member: Rosellinia necatrix quadrivirus 1


General Description

The genus Quadrivirus is the only genus in the family Quadriviridae. It is named because the genome has four segments.


Virions isometric (icosahedral), not enveloped, about 48 nm in diameter.


Quadripartite, linear double-stranded RNA, with segments ranging in size from 3.7 to 4.9 kbp. A terminal sequence of seven 5’- and fourteen 3’-nucleotides is strictly conserved in all segments.

Genus Genomic Organization

There are four RNAs, each encoding a single protein.

Type Member Genomic Organization

  • RNA1 (4.9 kbp) encodes a protein of 178 kDa (function unknown)
  • RNA2 (4.4 kbp) encodes a stuctural protein of 147 kDa
  • RNA3 (4.1 kbp) encodes a polymerase of 147 kDa
  • RNA4 (3.7kbp) encodes a second structural protein of 113 kDa