Notes on Genus: Quaranjavirus
enveloped spheres or pleomorphic
Type member: Quaranfil virus
The genus Quaranjavirus
is one of the genera in the family Orthomyxoviridae
. It is named from two of the constituent viruses (which are themselves named from their places of origin), Quaran
fil virus and J
toll virus. The viruses differ from those in most other genera of the family in having insect (tick) vectors and 6 monocistronic genome segments. Distantly related tick-borne viruses with 6 or 7 segments are classifed in the genus Thogotovirus
Virions spherical or pleomorphic, enveloped, 80-120 nm in diameter, with projections about 4-6 nm in diameter and 10-14 nm long.
Single-stranded negative sense RNA in 6 segments totalling about 11.5 kb. The segments do not have a genome-linked protein (VPg) at their 5'-terminus nor a 3'-polyA tail.
Genus Genomic Organization
There are 6 RNA segments, each of which encodes a single protein in the complementary sense.
Type Member Genomic Organization
There are 6 RNA segments:
- RNA1 (2421 nts) encodes a basic polymerase (PB2) of 84.8 kDa
- RNA2 (2403 nts) encodes an acid polymerase (PBA) of 78.4 kDa
- RNA3 (2386 nts) encodes a basic polymerase (PB1) of 88.2 kDa
- RNA4 (1726 nts) encodes a 59.2 kDa protein of unknown function
- RNA5 (1616 nts) encodes a putative glycoprotein of 57.3 kDa
- RNA6 (900 nts) encodes a 29.5 kDa protein of unknown function