Sequence of DPV Severe fever with thrombocytopenia syndrome virus
Phlebovirus HB29/China/2010 strain HB29 segment M, complete sequence.
ACC No: HM745931
Dated: 2011-08-10 | Length: 3378 | CRC: -162452912
ID HM745931; SV 1; linear; viral cRNA; STD; VRL; 3378 BP.
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AC HM745931;
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DT 09-MAR-2011 (Rel. 108, Created)
DT 10-AUG-2011 (Rel. 109, Last updated, Version 3)
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DE Phlebovirus HB29/China/2010 strain HB29 segment M, complete sequence.
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KW .
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OS SFTS virus HB29
OC Viruses; ssRNA negative-strand viruses; Bunyaviridae; Phlebovirus;
OC unclassified Phlebovirus.
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RN [1]
RP 1-3378
RX DOI; 10.1056/NEJMoa1010095.
RX PUBMED; 21410387.
RA Yu X.J., Liang M.F., Zhang S.Y., Liu Y., Li J.D., Sun Y.L., Zhang L.,
RA Zhang Q.F., Popov V.L., Li C., Qu J., Li Q., Zhang Y.P., Hai R., Wu W.,
RA Wang Q., Zhan F.X., Wang X.J., Kan B., Wang S.W., Wan K.L., Jing H.Q.,
RA Lu J.X., Yin W.W., Zhou H., Guan X.H., Liu J.F., Bi Z.Q., Liu G.H., Ren J.,
RA Wang H., Zhao Z., Song J.D., He J.R., Wan T., Zhang J.S., Fu X.P.,
RA Sun L.N., Dong X.P., Feng Z.J., Yang W.Z., Hong T., Zhang Y., Walker D.H.,
RA Wang Y., Li D.X.;
RT "Fever with thrombocytopenia associated with a novel bunyavirus in China";
RL N. Engl. J. Med. 364(16):1523-1532(2011).
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RN [2]
RP 1-3378
RA Li J., Sun Y., Liang M., Zhang Q., Lu J., Li C., Qu J., Zhan F., Li D.;
RT "A novel Phlebovirus related to severe fever with thrombocytopenia syndrome
RT (SFTS) in humans";
RL Unpublished.
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RN [3]
RP 1-3378
RA Li J., Sun Y., Liang M., Zhang Q., Lu J., Li C., Qu J., Zhan F., Li D.;
RT ;
RL Submitted (11-JUL-2010) to the INSDC.
RL Department of Viral Hemorrhagic Fever, National Institute for Viral
RL Diseases Control and Prevention, Changbai Road 155, Beijing 102206, China
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CC GenBank Accession Numbers HM745930-HM745932 represent sequences
CC from the 3 segments of Phlebovirus HB29/China/2010.
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FH Key Location/Qualifiers
FH
FT source 1. .3378
FT /organism="SFTS virus HB29"
FT /segment="M"
FT /host="Homo sapiens"
FT /strain="HB29"
FT /mol_type="viral cRNA"
FT /country="China"
FT /isolation_source="serum"
FT /collection_date="20-May-2010"
FT /db_xref="taxon:992212"
FT CDS 19. .3240
FT /codon_start=1
FT /product="membrane glycoprotein polyprotein"
FT /db_xref="GOA:F1BA47"
FT /db_xref="InterPro:IPR009878"
FT /db_xref="InterPro:IPR010826"
FT /db_xref="UniProtKB/TrEMBL:F1BA47"
FT /protein_id="ADZ04471.1"
FT /translation="MMKVIWFSSLICLVIQCSGDSGPIICAGPIHSNKSAGIPHLLGYS
FT EKICQIDRLIHVSSWLRNHSQFQGYVGQRGGRSQVSYYPAENSYSRWSGLLSPCDADWL
FT GMLVVKKAKESDMIVPGPSYKGKVFFERPTFDGYVGWGCGSGKSRTESGELCSSDSGTS
FT SGLLPSDRVLWIGDVACQPMTPIPEETFLELKSFSQSEFPDICKIDGIVFNQCEGESLP
FT QPFDVAWMDVGHSHKIIMREHKTKWVQESSSKDFVCYKEGTGPCSESEEKACKTSGSCR
FT GDMQFCKVAGCEHGEEASEAKCRCSLVHKPGEVVVSYGGTRVRPKCYGFSRMMATLEVN
FT PPEQRIGQCTGCHLECINGGVRLITLTSELRSATVCASHFCSSASSGKKSTEIHFHSGS
FT LVGKTAIHVKGALVDGTEFTFEGSCMFPDGCDAVDCTFCREFLKNPQCYPAKKWLFIII
FT VILLGYAGLMLLTNVLKAIGVWGSWVIAPVKLMFAIIKKLMRTVSCLVGKLMDRGRQVI
FT HEEIGENGEGNQDDVRIEMARPRRVRHWMYSPVILTILAIGLAEGCDEMVHADSKLVSC
FT RQGSGNMKECITTGRALLPAVNPGQEACLHFTAPGSPDSKCLKIKVKRINLKCKKSSSY
FT FVPDARSRCTSVRRCRWAGDCQSGCPPHFTSNSFSDDWAGKMDRAGLGFSGCSDGCGGA
FT ACGCFNAAPSCIFWRKWVENPHGIIWKVSPCAAWVPSAVIELTMPSGEVRTFHPMSGIP
FT TQVFKGVSVTYLGSDMEVSGLTDLCEIEELKSKKLALAPCNQAGMGVVGKVGEIQCSSE
FT ESARTIKKDGCIWNADLVGIELRVDDAVCYSKITSVEAVANYSAIPTTIGGLRFERSHD
FT SQGKISGSPLDITAIRGSFSVNYRGLRLSLSEITATCTGEVTNVSGCYSCMTGAKVSIK
FT LHSSKNSTAHVRCKGDETAFSVLEGVHSYIVRLSFDHAVVDEQCQLNCGGHESQVTLKG
FT NLIFLDVPKFVDGSYMQTYHSTVPTGANIPSPTDWLNALFGNGLSRWILGVIGVLLGGL
FT ALFFLIMFLLKLGTKQVFRSRTKLA"
FT sig_peptide 19. .75
FT mat_peptide 76. .1623
FT /product="Gn protein"
FT sig_peptide 1624. .1704
FT mat_peptide 1705. .3237
FT /product="Gc glycoprotein"
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SQ Sequence 3378 BP; 858 A; 697 C; 967 G; 856 T; 0 other;
hm745931 Length: 3378 10-AUG-2011 Type: N Check: 2597 ..
1 acacagagac ggccaacaat gatgaaagtc atctggttct cctctctgat
51 ctgcttagtc attcaatgca gtggggattc gggcccaatc atctgcgcag
101 gacccatcca ctcaaacaag agtgctggca taccccacct gcttggttac
151 tctgagaaga tttgtcagat agatcggctg atacatgttt cgtcatggct
201 caggaaccac tcgcaatttc aaggctacgt tgggcagcga ggtggacgct
251 ctcaggttag ctactaccca gctgagaatt cttactcgag gtggagtgga
301 cttctaagcc cctgtgatgc tgattggctt gggatgcttg tcgtgaagaa
351 ggctaaggag tctgatatga tagttcctgg gccttcatac aaggggaaag
401 tcttttttga acggccaact tttgatggat acgtaggctg gggctgtggc
451 agtgggaagt ctaggactga gtcaggagag ctctgcagtt cagactcagg
501 gacaagttct ggtcttctgc cctcggatag ggttctctgg ataggtgatg
551 ttgcttgtca gcctatgaca cccatccctg aggagacatt tctggagctg
601 aagagtttta gccaaagtga attcccagac atatgtaaaa ttgatggcat
651 tgtgttcaac cagtgtgagg gtgagagtct accccagccc tttgatgttg
701 catggatgga tgttggccac tctcataaga tcatcatgag ggagcacaag
751 accaaatggg tacaagagag ctcatccaag gattttgtgt gctacaagga
801 agggactgga ccttgttctg aatcagaaga aaaggcttgt aagaccagtg
851 gatcatgcag aggggacatg cagttttgca aggtggcagg ttgcgaacat
901 ggagaggagg catctgaggc caagtgtaga tgctcacttg tgcacaagcc
951 tggggaagtc gttgtgtcat atggagggac gcgtgtcaga ccaaagtgct
1001 acggtttctc cagaatgatg gcaacactgg aggtgaaccc accagagcaa
1051 aggattggtc aatgcactgg ctgccatcta gaatgcataa atgggggtgt
1101 gaggctaatc actctaacca gtgagctcag gtcagctact gtctgtgctt
1151 cccacttttg cagttctgcc tcaagtggta agaaaagcac ggagattcat
1201 ttccactcag gatcattggt tgggaaaaca gctatccatg tcaaaggggc
1251 attggtagat ggaactgaat tcacatttga gggtagttgc atgttcccag
1301 atggatgtga tgcagtggac tgcacattct gtcgtgagtt tctaaaaaat
1351 cctcagtgct accctgcaaa gaagtggctg ttcatcatta ttgtcatcct
1401 ccttggatat gcaggcctca tgttactcac caatgtcctt aaggcaattg
1451 gggtctgggg atcatgggta atagctccag tgaagctaat gtttgccatc
1501 ataaagaaac taatgagaac tgtgagctgc ttggtgggga aattgatgga
1551 taggggaagg caagtgatcc atgaggaaat aggggagaat ggggagggca
1601 accaagatga tgttaggatt gagatggcaa gacccagaag ggtaaggcat
1651 tggatgtact cacctgtcat cctgaccatt ctagcaatag ggcttgcaga
1701 gggctgtgat gagatggtcc atgctgattc taaacttgtt tcatgcagac
1751 aagggagcgg aaacatgaag gaatgcataa caactgggag ggcgcttctt
1801 cctgcggtga acccaggaca agaggcatgt ctgcacttca cagcacctgg
1851 gagtccggac tcaaaatgtc tcaaaattaa ggttaagagg atcaacctaa
1901 aatgtaagaa gtcatcatca tattttgttc ctgatgcccg gtccaggtgt
1951 acatcagtga ggagatgtcg ttgggcggga gactgccagt ctgggtgccc
2001 ccctcatttc acatccaact ccttttctga tgattgggca ggtaagatgg
2051 acagggctgg tcttggattc agtggctgct ctgatggatg tggaggagca
2101 gcctgcggct gctttaatgc ggccccttca tgcatcttct ggaggaaatg
2151 ggtggagaat ccacatggga tcatctggaa agtgtctcca tgcgccgcat
2201 gggtcccatc agcagttata gagctaacaa tgccctcagg tgaggtgagg
2251 acattccacc ccatgagcgg catccccaca caggtcttca agggtgtgag
2301 tgtaacttac ttgggctcag atatggaggt gtctggcttg actgacctgt
2351 gtgagataga agagctcaag tccaaaaagc tggcattagc tccctgcaac
2401 caggctggca tgggggttgt aggcaaggtt ggagagatac agtgcagtag
2451 cgaggagagt gcccgtacca taaaaaaaga tgggtgcata tggaacgcag
2501 acctcgtggg tatagagcta cgagtggatg acgctgtgtg ctactctaag
2551 attactagtg tggaggcagt tgcaaactac tctgccatac ccaccactat
2601 tggggggctg aggtttgaga gaagccatga cagccagggt aaaatatctg
2651 gtagccccct ggacatcaca gctataagag gatccttttc tgttaattat
2701 agaggccttc gattaagtct ctcagaaatt actgctactt gcacagggga
2751 ggtgacaaat gtgagtgggt gctattcctg catgacaggt gccaaagtct
2801 ccatcaaatt gcatagcagc aaaaatagca ctgcccatgt tagatgcaaa
2851 ggggatgaga ctgcattcag tgtcttggag ggagtccata gctacattgt
2901 ccgcctcagc tttgaccatg cagtagtcga tgagcaatgc cagctgaact
2951 gtgggggaca tgagagtcaa gtgactctta aaggcaacct catcttcctg
3001 gatgtcccaa aatttgtgga tggcagctac atgcagacat atcacagtac
3051 tgtgccaaca ggggcaaata tcccaagccc tacagattgg ctgaatgcct
3101 tgtttggcaa tgggctgagt aggtggatcc tgggggtgat aggggttcta
3151 ctggggggat tggctctctt tttcttgatc atgtttttgc tcaagctggg
3201 aacaaaacag gtatttcgat cgaggacgaa gctggcttag atgggcaaat
3251 ttctggtcta gtgaccctct gggagcagtg ctctcagggg agttggctca
3301 cagtgtgttt gtttcgtggt cctggctcac attcttagaa tatggaggtt
3351 ctattgaagt gttggccggt ctttgtgt