Sequence of DPV Norwalk virus
Norwalk calicivirus nonstructural polyprotein, 58 kd capsid protein and orf3 genes, complete cds.
ACC No: M87661
Dated: 2000-03-04 | Length: 7654 | CRC: -1707662437
!!NA_SEQUENCE 1.0
ID NWCRNA standard; RNA; VRL; 7654 BP.
XX
AC M87661;
XX
SV M87661.1
XX
DT 29-AUG-1992 (Rel. 33, Created)
DT 04-MAR-2000 (Rel. 63, Last updated, Version 5)
XX
DE Norwalk calicivirus nonstructural polyprotein, 58 kd capsid protein and
DE orf3 genes, complete cds.
XX
KW .
XX
OS Norwalk virus
OC Viruses; ssRNA positive-strand viruses, no DNA stage; Caliciviridae;
OC Norwalk-like viruses.
XX
RN [1]
RP 13-7654
RX MEDLINE; 93303939.
RA Jiang X., Wang M., Wang K., Estes M.K.;
RT "Sequence and genomic organization of Norwalk virus";
RL Virology 195(1):51-61(1993).
XX
RN [2]
RP 1-12
RX MEDLINE; 97037719.
RA Hardy M.E., Estes M.K.;
RT "Completion of the Norwalk virus genome sequence";
RL Virus Genes 12(3):287-290(1996).
XX
RN [3]
RP 13-7654
RA Estes M.K.;
RT ;
RL Submitted (09-AUG-1993) to the EMBL/GenBank/DDBJ databases.
RL M.K. Estes, Molecular Virology, Baylor College of Medicine, Houston, TX
RL 77006, USA
XX
RN [4]
RP 1-12
RA Hardy M.E.;
RT ;
RL Submitted (07-NOV-1995) to the EMBL/GenBank/DDBJ databases.
RL Michele E. Hardy, Molecular Virology, Baylor College of Medicine, Houston,
RL TX 77006, USA
XX
DR SPTREMBL; Q83883; Q83883.
DR SPTREMBL; Q83884; Q83884.
DR SPTREMBL; Q83885; Q83885.
XX
CC On Nov 13, 1995 this sequence version replaced gi:332545.
XX
FH Key Location/Qualifiers
FH
FT source 1. .7654
FT /db_xref="taxon:11983"
FT /organism="Norwalk virus"
FT CDS 5. .5374
FT /codon_start=1
FT /db_xref="SPTREMBL:Q83883"
FT /note="orf1; sequence homologies to 2C helicase, 3C
FT protease, and 3D RNA-dependent RNA polymerase of
FT picornavirus"
FT /product="nonstructural polyprotein"
FT /protein_id="AAB50465.1"
FT /translation="MMMASKDVVPTAASSENANNNSSIKSRLLARLKGSGGATSPPNSI
FT KITNQDMALGLIGQVPAPKATSVDVPKQQRDRPPRTVAEVQQNLRWTERPQDQNVKTWD
FT ELDHTTKQQILDEHAEWFDAGGLGPSTLPTSHERYTHENDEGHQVKWSAREGVDLGISG
FT LTTVSGPEWNMCPLPPVDQRSTTPATEPTIGDMIEFYEGHIYHYAIYIGQGKTVGVHSP
FT QAAFSITRITIQPISAWWRVCYVPQPKQRLTYDQLKELENEPWPYAAVTNNCFEFCCQV
FT MCLEDTWLQRKLISSGRFYHPTQDWSRDTPEFQQDSKLEMVRDAVLAAINGLVSRPFKD
FT LLGKLKPLNVLNLLSNCDWTFMGVVEMVVLLLELFGIFWNPPDVSNFIASLLPDFHLQG
FT PEDLARDLVPIVLGGIGLAIGFTRDKVSKMMKNAVDGLRAATQLGQYGLEIFSLLKKYF
FT FGGDQTEKTLKDIESAVIDMEVLSSTSVTQLVRDKQSARAYMAILDNEEEKARKLSVRN
FT ADPHVVSSTNALISRISMARAALAKAQAEMTSRMRPVVIMMCGPPGIGKTKAAEHLAKR
FT LANEIRPGGKVGLVPREAVDHWDGYHGEEVMLWDDYGMTKIQEDCNKLQAIADSAPLTL
FT NCDRIENKGMQFVSDAIVITTNAPGPAPVDFVNLGPVCRRVDFLVYCTAPEVEHTRKVS
FT PGDTTALKDCFKPDFSHLKMELAPQGGFDNQGNTPFGKGVMKPTTINRLLIQAVALTME
FT RQDEFQLQGPTYDFDTDRVAAFTRMARANGLGLISMASLGKKLRSVTTIEGLKNALSGY
FT KISKCSIQWQSRVYIIESDGASVQIKEDKQALTPLQQTINTASLAITRLKAARAVAYAS
FT CFQSAITTILQMAGSALVINRAVKRMFGTRTAAMALEGPGKEHNCRVHKAKEAGKGPIG
FT HDDMVERFGLCETEEEESEDQIQMVPSDAVPEGKNKGKTKKGRGRKNNYNAFSRRGLSD
FT EEYEEYKKIREEKNGNYSIQEYLEDRQRYEEELAEVQAGGDGGIGETEMEIRHRVFYKS
FT KSKKHQQEQRRQLGLVTGSDIRKRKPIDWTPPKNEWADDDREVDYNEKINFEAPPTLWS
FT RVTKFGSGWGFWVSPTVFITTTHVVPTGVKEFFGEPLSSIAIHQAGEFTQFRFSKKMRP
FT DLTGMVLEEGCPEGTVCSVLIKRDSGELLPLAVRMGAIASMRIQGRLVHGQSGMLLTGA
FT NAKGMDLGTIPGDCGAPYVHKRGNDWVVCGVHAAATKSGNTVVCAVQAGEGETALEGGD
FT KGHYAGHEIVRYGSGPALSTKTKFWRSSPEPLPPGVYEPAYLGGKDPRVQNGPSLQQVL
FT RDQLKPFADPRGRMPEPGLLEAAVETVTSMLEQTMDTPSPWSYADACQSLDKTTSSGYP
FT HHKRKNDDWNGTTFVGELGEQAAHANNMYENAKHMKPIYTAALKDELVKPEKIYQKVKK
FT RLLWGADLGTVVRAARAFGPFCDAIKSHVIKLPIKVGMNTIEDGPLIYAEHAKYKNHFD
FT ADYTAWDSTQNRQIMTESFSIMSRLTASPELAEVVAQDLLAPSEMDVGDYVIRVKEGLP
FT SGFPCTSQVNSINHWIITLCALSEATGLSPDVVQSMSYFSFYGDDEIVSTDIDFDPARL
FT TQILKEYGLKPTRPDKTEGPIQVRKNVDGLVFLRRTISRDAAGFQGRLDRASIERQIFW
FT TRGPNHSDPSETLVPHTQRKIQLISLLGEASLHGEKFYRKISSKVIHEIKTGGLEMYVP
FT GWQAMFRWMRFHDLGLWTGDRDLLPEFVNDDGV"
FT CDS 5358. .6950
FT /codon_start=1
FT /db_xref="SPTREMBL:Q83884"
FT /note="orf2"
FT /product="58 kd capsid protein"
FT /protein_id="AAB50466.1"
FT /translation="MMMASKDATSSVDGASGAGQLVPEVNASDPLAMDPVAGSSTAVAT
FT AGQVNPIDPWIINNFVQAPQGEFTISPNNTPGDVLFDLSLGPHLNPFLLHLSQMYNGWV
FT GNMRVRIMLAGNAFTAGKIIVSCIPPGFGSHNLTIAQATLFPHVIADVRTLDPIEVPLE
FT DVRNVLFHNNDRNQQTMRLVCMLYTPLRTGGGTGDSFVVAGRVMTCPSPDFNFLFLVPP
FT TVEQKTRPFTLPNLPLSSLSNSRAPLPISSIGISPDNVQSVQFQNGRCTLDGRLVGTTP
FT VSLSHVAKIRGTSNGTVINLTELDGTPFHPFEGPAPIGFPDLGGCDWHINMTQFGHSSQ
FT TQYDVDTTPDTFVPHLGSIQANGIGSGNYVGVLSWISPPSHPSGSQVDLWKIPNYGSSI
FT TEATHLAPSVYPPGFGEVLVFFMSKMPGPGAYNLPCLLPQEYISHLASEQAPTVGEAAL
FT LHYVDPDTGRNLGEFKAYPDGFLTCVPNGASSGPQQLPINGVFVFVSWVSRFYQLKPVG
FT TASSARGRLGLRR"
FT CDS 6950. .7588
FT /codon_start=1
FT /db_xref="SPTREMBL:Q83885"
FT /note="orf3; encodes small basic protein of unknown
FT function"
FT /protein_id="AAB50467.1"
FT /translation="MAQAIIGAIAASTAGSALGAGIQVGGEAALQSQRYQQNLQLQENS
FT FKHDREMIGYQVEASNQLLAKNLATRYSLLRAGGLTSADAARSVAGAPVTRIVDWNGVR
FT VSAPESSATTLRSGGFMSVPIPFASKQKQVQSSGISNPNYSPSSISRTTSWVESQNSSR
FT FGNLSPYHAEALNTVWLTPPGSTASSTLSSVPRGYFNTDRLPLFANNRR"
XX
SQ Sequence 7654 BP; 2108 A; 1792 C; 1883 G; 1871 T; 0 other;
M87661 Length: 7654 May 20, 2002 10:15 Type: N Check: 7252 ..
1 gtgaatgatg atggcgtcaa aagacgtcgt tcctactgct gctagcagtg
51 aaaatgctaa caacaatagt agtattaagt ctcgtctatt ggcgagactc
101 aagggttcag gtggggctac gtccccaccc aactcgataa agataaccaa
151 ccaagatatg gctctggggc tgattggaca ggtcccagcg ccaaaggcca
201 catccgtcga tgtccctaaa caacagaggg atagaccacc acggactgtt
251 gccgaagttc aacaaaattt gcgttggact gagagaccac aagaccagaa
301 tgttaagacg tgggatgagc ttgaccacac aacaaaacaa cagatacttg
351 atgaacacgc tgagtggttt gatgccggtg gcttaggtcc aagtacacta
401 cccactagtc atgaacggta cacacatgag aatgatgaag gccaccaggt
451 aaagtggtcg gctagggaag gtgtagacct tggcatatcc gggctcacga
501 cggtgtctgg gcctgagtgg aatatgtgcc cgctaccacc agttgaccaa
551 aggagcacga cacctgcaac tgagcccaca attggtgaca tgatcgaatt
601 ctatgaaggg cacatctatc attatgctat atacataggt caaggcaaga
651 cggtgggtgt acactcccct caagcagcct tctcaataac gaggatcacc
701 atacagccca tatcagcttg gtggcgagtc tgttatgtcc cacaaccaaa
751 acagaggctc acatacgacc aactcaaaga attagaaaat gaaccatggc
801 cgtatgccgc agtcacgaac aactgcttcg aattttgttg ccaggtcatg
851 tgcttggaag atacttggtt gcaaaggaag ctcatctcct ctggccggtt
901 ttaccacccg acccaagatt ggtcccgaga cactccagaa ttccaacaag
951 acagcaagtt agagatggtt agggatgcag tgctagccgc tataaatggg
1001 ttggtgtcgc ggccatttaa agatcttctg ggtaagctca aacccttgaa
1051 cgtgcttaac ttactttcaa actgtgattg gacgttcatg ggggtcgtgg
1101 agatggtggt cctcctttta gaactctttg gaatcttttg gaacccacct
1151 gatgtttcca actttatagc ttcactcctg ccagatttcc atctacaggg
1201 ccccgaggac cttgccaggg atctcgtgcc aatagtattg ggggggatcg
1251 gcttagccat aggattcacc agagacaagg taagtaagat gatgaagaat
1301 gctgttgatg gacttcgtgc ggcaacccag ctcggtcaat atggcctaga
1351 aatattctca ttactaaaga agtacttctt cggtggtgat caaacagaga
1401 aaaccctaaa agatattgag tcagcagtta tagatatgga agtactatca
1451 tctacatcag tgactcagct cgtgagggac aaacagtctg cacgggctta
1501 tatggccatc ttagataatg aagaagaaaa ggcaaggaaa ttatctgtca
1551 ggaatgccga cccacacgta gtatcctcta ccaatgctct catatcccgg
1601 atctcaatgg ctagggctgc attggccaag gctcaagctg aaatgaccag
1651 caggatgcgt cctgtggtca ttatgatgtg tgggccccct ggtataggta
1701 aaaccaaggc agcagaacat ctggctaaac gcctagccaa tgagatacgg
1751 cctggtggta aggttgggct ggtcccacgg gaggcagtgg atcattggga
1801 tggatatcac ggagaggaag tgatgctgtg ggacgactat ggaatgacaa
1851 agatacagga agactgtaat aaactgcaag ccatagccga ctcagccccc
1901 ctaacactca attgtgaccg aatagaaaac aagggaatgc aatttgtgtc
1951 tgatgctata gtcatcacca ccaatgctcc tggcccagcc ccagtggact
2001 ttgtcaacct cgggcctgtt tgccgaaggg tggacttcct tgtgtattgc
2051 acggcacctg aagttgaaca cacgaggaaa gtcagtcctg gggacacaac
2101 tgcactgaaa gactgcttca agcccgattt ctcacatcta aaaatggagt
2151 tggctcccca agggggcttt gataaccaag ggaatacccc gtttggtaag
2201 ggtgtgatga agcccaccac cataaacagg ctgttaatcc aggctgtagc
2251 cttgacgatg gagagacagg atgagttcca actccagggg cctacgtatg
2301 actttgatac tgacagagta gctgcgttca cgaggatggc ccgagccaac
2351 gggttgggtc tcatatccat ggcctcccta ggcaaaaagc tacgcagtgt
2401 caccactatt gaaggattaa agaatgctct atcaggctat aaaatatcaa
2451 aatgcagtat acaatggcag tcaagggtgt acattataga atcagatggt
2501 gccagtgtac aaatcaaaga agacaagcaa gctttgaccc ctctgcagca
2551 gacaattaac acggcctcac ttgccatcac tcgactcaaa gcagctaggg
2601 ctgtggcata cgcttcatgt ttccagtccg ccataactac catactacaa
2651 atggcgggat ctgcgctcgt tattaatcga gcggtcaagc gtatgtttgg
2701 tacccgtaca gcagccatgg cattagaagg acctgggaaa gaacataatt
2751 gcagggtcca taaggctaag gaagctggaa aggggcccat aggtcatgat
2801 gacatggtag aaaggtttgg cctatgtgaa actgaagagg aggagagtga
2851 ggaccaaatt caaatggtac caagtgatgc cgtcccagaa ggaaagaaca
2901 aaggcaagac caaaaaggga cgtggtcgca aaaataacta taatgcattc
2951 tctcgccgtg gtctgagtga tgaagaatat gaagagtaca aaaagatcag
3001 agaagaaaag aatggcaatt atagtataca agaatacttg gaggaccgcc
3051 aacgatatga ggaagaatta gcagaggtac aggcaggtgg tgatggtggc
3101 ataggagaaa ctgaaatgga aatccgtcac agggtcttct ataaatccaa
3151 gagtaagaaa caccaacaag agcaacggcg acaacttggt ctagtgactg
3201 gatcagacat cagaaaacgt aagcccattg actggacccc gccaaagaat
3251 gaatgggcag atgatgacag agaggtggat tataatgaaa agatcaattt
3301 tgaagctccc ccgacactat ggagccgagt cacaaagttt ggatcaggat
3351 ggggcttttg ggtcagcccg acagtgttca tcacaaccac acatgtagtg
3401 ccaactggtg tgaaagaatt ctttggtgag cccctatcta gtatagcaat
3451 ccaccaagca ggtgagttca cacaattcag gttctcaaag aaaatgcgcc
3501 ctgacttgac aggtatggtc cttgaagaag gttgccctga agggacagtc
3551 tgctcagtcc taattaaacg ggattcgggt gaactacttc cgctagccgt
3601 ccgtatgggg gctattgcct ccatgaggat acagggtcgg cttgtccatg
3651 gccaatcagg gatgttactg acaggggcca atgcaaaggg gatggatctt
3701 ggcactatac caggagactg cggggcacca tacgtccaca agcgcgggaa
3751 tgactgggtt gtgtgtggag tccacgctgc agccacaaag tcaggcaaca
3801 ccgtggtctg cgctgtacag gctggagagg gcgaaaccgc actagaaggt
3851 ggagacaagg ggcattatgc cggccacgag attgtgaggt atggaagtgg
3901 cccagcactg tcaactaaaa caaaattctg gaggtcctcc ccagaaccac
3951 tgccccccgg agtatatgag ccagcatacc tggggggcaa ggacccccgt
4001 gtacagaatg gcccatccct acaacaggta ctacgtgacc aactgaaacc
4051 ctttgcggac ccccgcggcc gcatgcctga gcctggccta ctggaggctg
4101 cggttgagac tgtaacatcc atgttagaac agacaatgga taccccaagc
4151 ccgtggtctt acgctgatgc ctgccaatct cttgacaaaa ctactagttc
4201 ggggtaccct caccataaaa ggaagaatga tgattggaat ggcaccacct
4251 tcgttggaga gctcggtgag caagctgcac acgccaacaa tatgtatgag
4301 aatgctaaac atatgaaacc catttacact gcagccttaa aagatgaact
4351 agtcaagcca gaaaagattt atcaaaaagt caagaagcgt ctactatggg
4401 gcgccgatct cggaacagtg gtcagggccg cccgggcttt tggcccattt
4451 tgtgacgcta taaaatcaca tgtcatcaaa ttgccaataa aagttggcat
4501 gaacacaata gaagatggcc ccctcatcta tgctgagcat gctaaatata
4551 agaatcattt tgatgcagat tatacagcat gggactcaac acaaaataga
4601 caaattatga cagaatcctt ctccattatg tcgcgcctta cggcctcacc
4651 agaattggcc gaggttgtgg cccaagattt gctagcacca tctgagatgg
4701 atgtaggtga ttatgtcatc agggtcaaag aggggctgcc atctggattc
4751 ccatgtactt cccaggtgaa cagcataaat cactggataa ttactctctg
4801 tgcactgtct gaggccactg gtttatcacc tgatgtggtg caatccatgt
4851 catatttctc attttatggt gatgatgaga ttgtgtcaac tgacatagat
4901 tttgacccag cccgcctcac tcaaattctc aaggaatatg gcctcaaacc
4951 aacaaggcct gacaaaacag aaggaccaat acaagtgagg aaaaatgtgg
5001 atggactggt cttcttgcgg cgcaccattt cccgtgatgc ggcagggttc
5051 caaggcaggt tagatagggc ttcgattgaa cgccaaatct tctggacccg
5101 cgggcccaat cattcagatc catcagagac tctagtgcca cacactcaaa
5151 gaaaaataca gttgatttca cttctagggg aagcttcact ccatggtgag
5201 aaattttaca gaaagatttc cagcaaggtc atacatgaaa tcaagactgg
5251 tggattggaa atgtatgtcc caggatggca ggccatgttc cgctggatgc
5301 gcttccatga cctcggattg tggacaggag atcgcgatct tctgcccgaa
5351 ttcgtaaatg atgatggcgt ctaaggacgc tacatcaagc gtggatggcg
5401 ctagtggcgc tggtcagttg gtaccggagg ttaatgcttc tgaccctctt
5451 gcaatggatc ctgtagcagg ttcttcgaca gcagtcgcga ctgctggaca
5501 agttaatcct attgatccct ggataattaa taattttgtg caagcccccc
5551 aaggtgaatt tactatttcc ccaaataata cccccggtga tgttttgttt
5601 gatttgagtt tgggtcccca tcttaatcct ttcttgctcc atctatcaca
5651 aatgtataat ggttgggttg gtaacatgag agtcaggatt atgctagctg
5701 gtaatgcctt tactgcgggg aagataatag tttcctgcat accccctggt
5751 tttggttcac ataatcttac tatagcacaa gcaactctct ttccacatgt
5801 gattgctgat gttaggactc tagaccccat tgaggtgcct ttggaagatg
5851 ttaggaatgt tctctttcat aataatgata gaaatcaaca aaccatgcgc
5901 cttgtgtgca tgctgtacac ccccctccgc actggtggtg gtactggtga
5951 ttcttttgta gttgcagggc gagttatgac ttgccccagt cctgatttta
6001 atttcttgtt tttagtccct cctacggtgg agcagaaaac caggcccttc
6051 acactcccaa atctgccatt gagttctctg tctaactcac gtgcccctct
6101 cccaatcagt agtatcggca tttccccaga caatgtccag agtgtgcagt
6151 tccaaaatgg tcggtgtact ctggatggcc gcctggttgg caccacccca
6201 gtttcattgt cacatgttgc caagataaga gggacctcca atggcactgt
6251 aatcaacctt actgaattgg atggcacacc ctttcaccct tttgagggcc
6301 ctgcccccat tgggtttcca gacctcggtg gttgtgattg gcatatcaat
6351 atgacacagt ttggccattc tagccagacc cagtatgatg tagacaccac
6401 ccctgacact tttgtccccc atcttggttc aattcaggca aatggcattg
6451 gcagtggtaa ttatgttggt gttcttagct ggatttcccc cccatcacac
6501 ccgtctggct cccaagttga cctttggaag atccccaatt atgggtcaag
6551 tattacggag gcaacacatc tagccccttc tgtatacccc cctggtttcg
6601 gagaggtatt ggtctttttc atgtcaaaaa tgccaggtcc tggtgcttat
6651 aatttgccct gtctattacc acaagagtac atttcacatc ttgctagtga
6701 acaagcccct actgtaggtg aggctgccct gctccactat gttgaccctg
6751 ataccggtcg gaatcttggg gaattcaaag cataccctga tggtttcctc
6801 acttgtgtcc ccaatggggc tagctcgggt ccacaacagc tgccgatcaa
6851 tggggtcttt gtctttgttt catgggtgtc cagattttat caattaaagc
6901 ctgtgggaac tgccagctcg gcaagaggta ggcttggtct gcgccgataa
6951 tggcccaagc cataattggt gcaattgctg cttccacagc aggtagtgct
7001 ctgggagcgg gcatacaggt tggtggcgaa gcggccctcc aaagccaaag
7051 gtatcaacaa aatttgcaac tgcaagaaaa ttcttttaaa catgacaggg
7101 aaatgattgg gtatcaggtt gaagcttcaa atcaattatt ggctaaaaat
7151 ttggcaacta gatattcact cctccgtgct gggggtttga ccagtgctga
7201 tgcagcaaga tctgtggcag gagctccagt cacccgcatt gtagattgga
7251 atggcgtgag agtgtctgct cccgagtcct ctgctaccac attgagatcc
7301 ggtggcttca tgtcagttcc cataccattt gcctctaagc aaaaacaggt
7351 tcaatcatct ggtattagta atccaaatta ttccccttca tccatttctc
7401 gaaccactag ttgggtcgag tcacaaaact catcgagatt tggaaatctt
7451 tctccatacc acgcggaggc tctcaataca gtgtggttga ctccacccgg
7501 ttcaacagcc tcttctacac tgtcttctgt gccacgtggt tatttcaata
7551 cagacaggtt gccattattc gcaaataata ggcgatgatg ttgtaatatg
7601 aaatgtgggc atcatattca tttaattagg tttaattagg tttaatttga
7651 tgtt