Notes on Genus: Ephemerovirus

enveloped bacilliform

Type member: Bovine ephemeral fever virus

Contents

• Members of this Genus
• General Description
• Morphology
• Electron Micrograph
• Genome
• Genus Genomic Organization
• Genome Map
• Type Member Genomic Organization
• All Known Sequences
• Curated Sequences

General Description

This is one of the animal virus genera in the family Rhabdoviridae. The genus is characterised by its bacilliform, enveloped, particles which contain a monopartite ssRNA genome that is more than 12kb in size. The name is taken from the type member.

Morphology

Virions are bullet- or cone-shaped, about 140-200 nm long and 60-80 nm in diameter.

Genome

Monopartite, linear, single-stranded, negative sense RNA, about 15000 nucleotides long.

Genus Genomic Organization

There are the five structural proteins common to all members of the family and several additional genes, encoding a tranmembrane glycoprotein and other proteins of unknown function, between the G and L genes.

Type Member Genomic Organization

The genes are listed here in their order on the template strand (i.e. from 3' to 5' with respect to the virion strand):

ORF	  Gene    	Product	Function
1	N	49.1 kDa	Coat protein (nucleocapsid)
2	P	32.2 kDa	Polymerase-associated phosphoprotein
3	P'	5.8 kda	P protein overlapping ORF2
4	M	25.5 kda	Matrix protein
5	G	72.3 kda	Glycoprotein
6	GNS	68.8 kDa	Transmembrane glycoprotein
7	alpha 1	10.7 kDa	unknown function
8	alpha 2	14.2 kDa	unknown function
9	alpha 3	5.7 kDa	unknown function
10	beta	12.3 kDa	unknown function
11	gamma	13.4 kDa	unknown function
12	L	249.8 kDa  	Polyprotein with replicase and other functions