Notes on Genus: Ephemerovirus

enveloped bacilliform
enveloped bacilliform

Type member: Bovine ephemeral fever virus


General Description

This is one of the animal virus genera in the family Rhabdoviridae. The genus is characterised by its bacilliform, enveloped, particles which contain a monopartite ssRNA genome that is more than 12kb in size. The name is taken from the type member.


Virions are bullet- or cone-shaped, about 140-200 nm long and 60-80 nm in diameter.


Monopartite, linear, single-stranded, negative sense RNA, about 15000 nucleotides long.

Genus Genomic Organization

There are the five structural proteins common to all members of the family and several additional genes, encoding a tranmembrane glycoprotein and other proteins of unknown function, between the G and L genes.

Type Member Genomic Organization

The genes are listed here in their order on the template strand (i.e. from 3' to 5' with respect to the virion strand):
ORF  Gene     ProductFunction
1 N 49.1 kDaCoat protein (nucleocapsid)
2 P32.2 kDaPolymerase-associated phosphoprotein
3 P' 5.8 kdaP protein overlapping ORF2
4 M 25.5 kdaMatrix protein
5 G72.3 kda Glycoprotein
6 GNS68.8 kDaTransmembrane glycoprotein
7 alpha 110.7 kDaunknown function
8 alpha 214.2 kDaunknown function
9 alpha 35.7 kDaunknown function
10 beta12.3 kDaunknown function
11 gamma13.4 kDaunknown function
12 L249.8 kDa   Polyprotein with replicase and other functions