Notes on Genus: Mycoreovirus

icosahedra

Type member: Mycoreovirus 1

Contents

• Members of this Genus
• General Description
• Morphology
• Electron Micrograph
• Genome
• Genus Genomic Organization
• Genome Map
• Type Member Genomic Organization
• All Known Sequences
• Curated Sequences

General Description

This genus is the only one in the family Reoviridae to consist of viruses that infect fungi (hence the name).

Morphology

Virions isometric (icosahedral), c.80 nm in diameter, with two concentric capsid shells surrounding a core that contains 12 surface projections that connect the inner and outer capsid layers.

Genome

Linear, double stranded RNA in 11 or 12 segments. Each virion contains a single copy of the entire genome. The 3' terminus has neither a poly(A) tract nor a tRNA-like structure. All RNA segments have highly conserved nucleotide sequences at the 3'- and 5'-termini.

Genus Genomic Organization

Each segment contains a single ORF with the RNA polymerase translated from the largest segment.

Type Member Genomic Organization

Each segment has one open reading frame:

Segment    	   Size (nt)  	  Protein (kDa)  
1	4127	Polymerase, 151.8
2	3846	137.6
3	3258	120.8
4	2269	79.8
5	2056	72.7
6	2023	NTP-binding, 73.4
7	1539	51.2
8	1536	54.1
9	1072	32.9
10	975	27.8
11	732	11.5