Notes on Genus: Sigmavirus

enveloped bacilliform

Type member: Drosophila melanogaster sigmavirus

Contents

• Members of this Genus
• General Description
• Morphology
• Electron Micrograph
• Genome
• Genus Genomic Organization
• Genome Map
• Type Member Genomic Organization
• All Known Sequences
• Curated Sequences

General Description

This is one of the animal virus genera in the family Rhabdoviridae. As in other genera, there are bacilliform, enveloped, particles which contain a monopartite ssRNA genome. Members infect invertebrates and are transmitted vertically through eggs and sperm. The name is taken from the type member.

Morphology

Virions are bullet- or cone-shaped, about 140-200 nm long and 75 nm in diameter.

Genome

Monopartite, linear, single-stranded, negative sense RNA, about 13000 nucleotides long.

Genus Genomic Organization

There are the five structural proteins common to all members of the family and an additional gene (X) encoding a protein of unknown function situated between the P and M genes.

Type Member Genomic Organization

The genes are listed here in their order on the template strand (i.e. from 3' to 5' with respect to the virion strand):

ORF	  Gene    	Product	Function
1	N	50.8 kDa	Coat protein (nucleocapsid)
2	P	35.3 kDa	Polymerase-associated phosphoprotein
3	X	33.8 kda	Protein of unknown function
4	M	25.8 kda	Matrix protein
5	G	63.4kda	Glycoprotein
6	L	241.3 kDa  	Polyprotein with replicase and other functions