Notes on Genus: Alphatorquevirus
Type member: Torque teno virus 1
This is one of the genera in the family Anelloviridae
and contains viruses previously classified as Torque teno virus
. The viruses infect primates and have genomes of up to 3.9 kb (larger than in some of the other genera). The genus name is partly derived from the latin torques
, for necklace which reflects the circular nature of the genome.
Virions isometric (icosahedral), not enveloped, 19-27 nm in diameter.
Monopartite circular single-stranded DNA of 3.1-3.9 kb.
Genus Genomic Organization
There are two major overlapping ORFs encoding a replication-associated protein and a (larger) coat protein. Further products may also be generated by splicing of an intron. Additional ORFs may be present in some isolates.
Type Member Genomic Organization
There are two major overlapping ORFs:
- ORF1: 90 kDa, Coat protein
- ORF2: 21 kDa, Replication protein (one or two proteins of about 30 kDa may also be generated by splicing of introns)