Notes on Genus: Thetatorquevirus

icosahedra
icosahedra

Type member: Torque teno canis virus

Contents

General Description

This is one of the genera in the family Anelloviridae and contains viruses of dogs with a genome of 2.8 kb. The genus name is partly derived from the latin torques, for necklace which reflects the circular nature of the genome.

Morphology

Virions isometric (icosahedral), not enveloped, 19-27 nm in diameter.

Genome

Monopartite circular single-stranded DNA of 2.8 kb.

Genus Genomic Organization

There are two major overlapping ORFs encoding a replication-associated protein and a (larger) coat protein. Further products may also be generated by splicing of an intron.

Type Member Genomic Organization

There are two major overlapping ORFs:
  • ORF1: 68 kDa, Coat protein
  • ORF2: 11 kDa, Replication protein (a protein of about 27 kDa may also be generated by splicing of an intron)