Notes on Genus: Gammatorquevirus
icosahedra
Type member: Torque teno midi virus 1
Contents
General Description
This is one of the genera in the family
Anelloviridae and contains viruses previously described as Torque teno midi virus. The viruses infect primates and have genomes of up to 3.2 kb (intermediate in size between those in the genera
Alphatorquevirus and
Betatorquevirus). The genus name is partly derived from the latin
torques, for necklace which reflects the circular nature of the genome.
Morphology
Virions isometric (icosahedral), not enveloped, 19-27 nm in diameter.
Genome
Monopartite circular single-stranded DNA of 3.2 kb.
Genus Genomic Organization
There are two major overlapping ORFs encoding a replication-associated protein and a (larger) coat protein. Further products may also be generated by splicing of an intron.
Type Member Genomic Organization
There are two major overlapping ORFs:
- ORF1: 80 kDa, Coat protein
- ORF2: 14 kDa, Replication protein (one or two proteins of about 29 kDa may also be generated by splicing of introns)